4 documents found, page 1 of 1

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Estudo do potencial antioxidante, anti-inflamatório e cicatrizante de Bauhinia ...

Rodrigues, Raphael de Oliveira

Bauhinia ungulata L. is a species native to Brazil and little is known in respect to its pharmacological properties. Studies carried out with the plant resulted in the isolation and identification of some chemical compounds, among them, flavonoids, bibenzyls, triterpenoids and oxepinic derivatives, for example. The present work aimed to investigate the antioxidant, immunomodulatory, antimicrobial and wound heal...

Date: 2019   |   Origin: Oasisbr

Antioxidant and anti-inflammatory activities of Bauhinia ungulata L. (Fabaceae)...

Rodrigues, Raphael de Oliveira; Yaochite, Juliana Navarro Ueda; Braga, Milena Aguiar; Sousa, Amanda Ribeiro de; Sasahara, Greyce Luri

Objective: The present study aimed to investigate the antioxidant, immunomodulatory and antimicrobial activities of Bauhinia ungulata L. Method: A flavonoid-rich fraction was obtained from the Bauhinia ungulata L stem, called the ethyl acetate fraction of Bauhinia ungulata (FABU). The total antioxidant capacity of the FABU was determined through the phosphomolibdenium reduction method. For the evaluation of its...

Date: 2019   |   Origin: Oasisbr

Association of IL10 , IL4 , IFNG , and CTLA4 gene polymorphisms with efavirenz ...

Rodrigues, Raphael de Oliveira; Rabenhorst, Silvia Helena Barem; Carvalho, Paulo Germano de; Sasahara, Greyce Luri; Vasconcelos, Luciana Mabel Ferreira

SUMMARY: We evaluated interleukin-10 ( IL10 ) - 592 C / A, IL4 - 589 C / T, interferon gamma ( IFNG ) + 874 A / T, cytotoxic T-lymphocyte-associated antigen 4 ( CTLA4 ) + 49 A / G gene polymorphisms associated with efavirenz hypersensitivity reaction. A total of 63 human immunodeficiency virus-positive patients under treatment at a public hospital were included in the study, of whom 21 presented with efavirenz ...

Date: 2017   |   Origin: Oasisbr

Polymorphism of IL10, IL4, CTLA4, and DAO genes in cross-reactive nonsteroidal ...

Vasconcelos, Luciana Mabel Ferreira; Rodrigues, Raphael de Oliveira; Albuquerque, Andressa Almeida; Barroso, Gabrielle Dantheias; Sasahara, Greyce Luri

Our aim was to evaluate genetic polymorphism of molecules involved in immunoregulatory/allergic processes in patients who presented with cutaneous hypersensitivity caused by chemically unrelated nonsteroidal anti-inflammatory drugs. Polymorphisms at IL10 (–1082 G>A), IL4 (–589 C>T), CTLA4 (+49A>G), and DAO (+8956 C>G) genes were studied in 55 cases and 97 controls by the polymerase chain reaction-restriction fr...

Date: 2017   |   Origin: Oasisbr

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