19 documents found, page 1 of 2

Effects of (−)-6,6′-dinitrohinokinin on adult worms of Schistosoma mansoni: A p...

Made available in DSpace on 2022-04-28T19:03:53Z (GMT). No. of bitstreams: 0 Previous issue date: 2016-05-01; Schistosomiasis, a chronic disease that affects million people worldwide, is caused by trematodeflukes of the genus Schistosoma. The lack of an anti-schistosomiasis vaccine and massive monother-apy with praziquantel reinforces the need for search and development of new therapeutic drugs.Recently, we dem...

Deubiquitinating enzymes as possible drug targets for schistosomiasis

Inhibition of 19S proteasome deubiquitinating activity in Schistosoma mansoni a...

Schistosoma mansoni heat shock protein 70 elicits an early humoral immune respo...

Made available in DSpace on 2019-09-11T20:58:42Z (GMT). No. of bitstreams: 0 Previous issue date: 2002; A study was undertaken to search for DNA recombinant Schistosoma mansoni proteins responsible for eliciting an antibody response from the host at a very early phase after infection. A S. mansoni adult worm cDNA expression library was screened using pooled sera from baboons with four weeks of infection. Based ...

Effect of phytopharmaceutical Mentaliv®on neutrophil and eosinophil functions

Mentha piperita L. has been studied by our group as a possible phytopharmacological drug for treatment of diseases that promote intense inflammatory responses mediated by eosinophils and neutrophils. Thus, the analysis of antioxidant effects and cytokine production by these cells is important to understand the effect of these compounds on the innate and effector phase of adaptive immune response. In this way, a...

In vitro and in vivo anthelmintic activity of (-)-6,6 '-dinitrohinokinin agains...

Made available in DSpace on 2018-11-26T16:16:29Z (GMT). No. of bitstreams: 0 Previous issue date: 2015-09-01; Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); The chemotherapy of schistosomiasis relies on the use of praziquantel. However, concerns over drug resistance have encouraged the search for new drug leads. This paper is ...

Molecular characterization of transport lectin vesicular integral membrane prot...

Effects of proteasome inhibitor MG-132 on the parasite Schistosoma mansoni

Uncovering Notch pathway in the parasitic flatworm Schistosoma mansoni

Proteasome stress responses in Schistosoma mansoni