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Enalapril in combination with benznidazole reduces cardiac inflammation and cre...

Penitente, Arlete Rita; Leite, Ana Luísa Junqueira; Costa, Guilherme de Paula; Shrestha, Deena; Horta, Aline Luciano; Natali, Antônio J.

The protozoan Trypanosoma cruzi triggers an inflammatory process in mammalian heart causing events such as fibrosis, changes in the architecture and functionality in this organ. Enalapril, an angiotensin II-converting enzyme inhibitor, is a drug prescribed to ameliorate this heart dysfunction, and appears to exert a potential role in immune system regulation. Our aim was to evaluate the chronic cardiac inflamma...

Date: 2018   |   Origin: Oasisbr


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