3 documents found, page 1 of 1
Nodal Response After Neoadjuvant Chemotherapy and Potential Targets for Axillar...
Pereira Gonçalves, Beatriz; Costeira, Beatriz; Girão, Maria do Carmo; Oom, Rodrigo; Sousa Costa, Cristina; Vargas Moniz, João; Abecasis, NunoIntroduction: Neoadjuvant chemotherapy (NAC) has the potential for tumor downstaging and surgery de-escalation. In the axilla, this approach is less established, especially in cN+→ycN0. Targeted axillary dissection is an option, but difficult to concretize. We aim to identify biological factors associated with nodal pathological complete response (pCR) and recognize potential candidates for a more conservative ...
Breast Implant-Associated Anaplastic Large Cell Lymphoma: Two Distinct Clinical...
Miranda, Pedro; Moita, Filipa; Vargas Moniz, João; Rodrigues dos Santos, CatarinaBreast implant-associated anaplastic large cell lymphoma (BIA-ALCL) is a rare CD30 positive T cell lymphoma whose incidence has recently increased. Until 2020, 733 cases of BIA-ALCL and 36 deaths have been reported around the world, with only one confirmed case in Portugal. The authors describe two clinical cases of BIA-ALCL after breast cancer reconstruction using macrotextured implants. Case 1: A 45-year-old ...
The Use of Sentinel Lymph Node Biopsy in BRCA1/2 Mutation Carriers Undergoing P...
Câmara, Sara; Pereira, Daniela; André, Saudade; Mira, Beatriz; Vaz, Fátima; Oom, Rodrigo; Marques, José Carlos; Leal de Faria, JoãoSentinel lymph node biopsy in prophylactic mastectomy is controversial. It avoids lymphadenectomy in occult carcinoma but is associated with increased morbidity. Women with BRCA mutations have a higher incidence of occult carcinoma and our objective was to assess the clinical utility of sentinel lymph node biopsy when these women undergo prophylactic mastectomy.