10 documents found, page 1 of 1

The Association between Childhood Obesity and Cardiovascular Changes in 10 Year...

The increasing prevalence of overweight and obesity is a worldwide problem, with several well-known consequences that might start to develop early in life during childhood. The present research based on data from children that have been followed since birth in a previously established cohort study (Generation XXI, Porto, Portugal), taking advantage of State-of-the-Art (SoA) data science techniques and methods, ...

Investigação Clínica da Iniciativa do Investigador em Portugal: Identificação d...

The identification of the Rosa S-locus and implications on the evolution of the...

In Rosaceae species, two gametophytic self-incompatibility (GSI) mechanisms are described, the Prunus self-recognition system and the Maleae (Malus/Pyrus/Sorbus) non-self- recognition system. In both systems the pistil component is a S-RNase gene, but from two distinct phylogenetic lineages. The pollen component, always a F-box gene(s), in the case of Prunus is a single gene, and in Maleae there are multiple ge...

Spatially explicit analysis reveals complex human genetic gradients in the Iber...

The Iberian Peninsula is a well-delimited geographic region with a rich and complex human history. However, the causes of its genetic structure and past migratory dynamics are not yet fully understood. In order to shed light on them, here we evaluated the gene flow and genetic structure throughout the Iberian Peninsula with spatially explicit modelling applied to a georeferenced genetic dataset composed of geno...

Prognostic Effect of Renal Function in Ambulatory Patients With Heart Failure a...

Background: Chronic kidney disease is a frequent comorbidity in heart failure (HF), associated with increased mortality. The impact of temporal evolution of kidney function in HF prognosis is largely unknown. We evaluated the effect of renal function over time in all-cause mortality among ambulatory patients with HF. Methods: We retrospectively analyzed data from 560 patients with HF with left ventricular systo...

Evaluating the Neolithic Expansion at Both Shores of the Mediterranean Sea

During the Neolithic, human populations underwent cultural and technological developments that led to an agricultural revolution. Although the population genetics and evolution of European Neolithic populations have been extensively studied, little is known regarding the Neolithic expansion in North Africa with respect to Europe. One could expect that the different environmental and geological conditions at bot...

Higher BMI in heart failure patients is associated with longer survival only in...

Aims Obesity and diabetes are associated with an increased cardiovascular risk and mortality. Paradoxically, higher BMI is associated with longer survival in heart failure patients. The association between BMI and risk of death in heart failure patients depends on diabetes history. Methods We conducted a retrospective cohort study on 503 ambulatory systolic heart failure patients attending a heart failure clini...

Association between plasma leptin and adiponectin levels and diastolic function...

Background: Total and visceral obesity are associated with subclinical diastolic dysfunction (DD) and heart failure. Adipose tissue is an endocrine organ able to secrete adipokines involved in several obesity-associated diseases. We aimed to evaluate the association between leptin and adiponectin levels and diastolic function.Methods and results: Within a population-based study (EPIPorto), 556 individuals were ...

Percurso hospitalar: fratura da extremidade proximal do fémur

Gastric ascariasis: a rare cause of upper gastrointestinal bleeding