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Hypomagnesemia: a Potential Underlooked Cause of Persistent Vitamin D Deficienc...

Matias, P; Ávila, G; Ferreira, AC; Laranjinha, I; Ferreira, A

Magnesium and vitamin D play important roles in most cells of the body. These nutrients act in a coordinated fashion to maintain physiologic functions of various organs, and their abnormal balance could adversely affect these functions. Therefore, deficient states of both nutrients may lead to several chronic medical conditions and increased cardiovascular and all-cause mortality. Chronic kidney disease (CKD) p...


A large outbreak of Legionnaires’ Disease in an industrial town in Portugal

George, F; Shivaji, T; Pinto, CS; Serra, LA; Valente, J; Albuquerque, MJ; Vicêncio, PC; San-Bento, A; Diegues, P; Nogueira, PJ; Marques, T; Rebelo, H

Background We describe the investigation and control of an outbreak of Legionnaires’ disease in Portugal in October, November and December 2014. Methods Confirmed cases were individuals with pneumonia, laboratory evidence of Legionella pneumophila serogroup 1 and exposure, by residence, occupational or leisure to the affected municipalities. 49 possible sources were reduced to four potential sources, all indust...


Mineral and Bone Disease (MBD) on a Kidney Transplant Patient

Birne, R; Adragão, T; Ferreira, A; Dickson, J; Silva, R; Casqueiro, A; Oliveira, R; Martins, AR; Torres, J; Matias, P; Branco, P; Jorge, C; Weigert, A

A 50-year-old post-menopausal recipient of a kidney allograft with bone pain, osteoporosis, persistent hypercalcaemia and elevated parathormone (PTH) levels, despite a satisfactory graft function, was treated with bisphosphonates and cinacalcet starting, respectively, 5 and 6 months after renal transplantation (RT). Sixteen months after treatment, there was improvement of bone mineral density (BMD) measured by ...


Characterisation by adsorption of various organic vapours of the porosity of fr...

Russo, PA; Ribeiro Carrott, MML; Carrott, PJM; Matias, P; Lopes, JM; Guisnet, M; Ramôa Ribeiro, F

The microporosity of H-MCM-22 samples, fresh and deactivated by coke during methylcyclohexane transformation at 350 C for 10 h, was characterised by adsorption of nitrogen and organic molecules of different size, namely, p- and o-xylenes, mesitylene and methylcyclohexane. Nitrogen adsorption was also carried out on the fresh sample after pre-adsorption of the hydrocarbons. All of these can fit the outer 12 MR c...


Diabetes Mellitus and Renal Disease: When to Perform a Renal Biopsy?

Matias, P; Viana, H; Carvalho, F; Ribeiro Santos, J

Background: Several studies suggest that nondiabetic renal disease (NDRD) is common in patients with diabetes mellitus. The aim of this analysis of renal biopsies in diabetic patients was (a) to assess the prevalence and type of NDRD and (b) to identify its clinical and laboratory predictors. Methods: This retrospective study analysed clinical and laboratory data and biopsy findings in diabetic patients observe...


Brain Natriuretic Peptide Levels Predict Morbidity and Mortality in Haemodialys...

Matias, P; Jorge, C; Aires, I; Lage, H; Gil, C; Gomes, F; Arranhado, E; Ferreira, A

Background: Brain natriuretic peptide is a predictor of mortality in multiple cardiovascular diseases but its value in patients with chronic kidney disease is still a matter of debate. Patients and methods: We studied 48 haemodialysis patients with mean age 70.0±13.9 years,62.5% female, 43.8% diabetics, with a mean haemodialysis time of 38.1±29.3 months. To evaluate the role of brain natriuretic peptide as a pr...


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