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Protein-based films functionalized with a truncated antimicrobial peptide seque...

da Costa, André; Pereira, Ana M.; Sampaio, Paula; Rodriguez-Cabello, Jose Carlos; Gomes, Andreia C; Casal, Margarida; Machado, Raul

The increasing bacterial resistance to antibiotics is driving strong demand for new antimicrobial biomaterials. This work describes the fabrication of free-standing films exhibiting antimicrobial properties by combining, in the same polypeptide chain, an elastin-like recombinamer comprising 200 repetitions of the pentamer VPAVG (A200) and an 18-amino-acid truncated variant of the antimicrobial peptide BMAP-28, ...

Date: 2021   |   Origin: RepositóriUM - Universidade do Minho
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