21 documents found, page 1 of 3
Germline variants in DNA repair genes are associated with young-onset head and ...
Cury, Sarah Santiloni [UNESP]; Miranda, Priscila Mayrink de; Marchi, Fabio Albuquerque; Canto, Luisa Matos do; Chulam, Thiago CelestinoMade available in DSpace on 2022-04-28T19:45:14Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-11-01; The genetic predisposition to head and neck carcinomas (HNSCC) and how the known risk factors (papillomavirus infection, alcohol, and tobacco consumption) contribute to the early-onset disease are barely explored. Although HNSCC at early onset is rare, its frequency is increasing in recent years. Germli...
Master regulators of epithelial-mesenchymal transition and wnt signaling pathwa...
Calanca, Naiade [UNESP]; Binato, Sara Martoreli Silveira; Silva, Sabrina Daniela da; Brentani, Helena Paula; Sennes, Luiz UbirajaraMade available in DSpace on 2022-04-29T08:45:57Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-09-01; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES); Juvenile nasopharyngeal angiofibroma (JNA) is a rare fibrovascular benign tumor showing an invasive growth pattern and affecting mainly male adolescents. We investigated th...
Xeroderma pigmentosum: Low prevalence of germline XPA mutations in a brazilian ...
Santiago, Karina Miranda; De Nóbrega, Amanda França; Rocha, Rafael Malagoli; Rogatto, Silvia Regina; Achatz, Maria IsabelMade available in DSpace on 2022-04-29T08:45:01Z (GMT). No. of bitstreams: 0 Previous issue date: 2015-04-01; Xeroderma pigmentosum (XP) is a rare autosomal recessive disorder characterized by DNA repair defects that cause photophobia, sunlight-induced cancers, and neurodegeneration. Prevalence of germline mutations in the nucleotide excision repair gene XPA vary significantly in different populations. No Brazi...
Drug repositioning based on the reversal of gene expression signatures identifi...
Carvalho, Robson Francisco [UNESP]; Canto, Luisa Matos Do; Cury, Sarah Santiloni [UNESP]; Hansen, Torben Frøstrup; Jensen, Lars HenrikMade available in DSpace on 2022-05-01T09:47:31Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-11-01; National Cancer Institute; National Heart, Lung, and Blood Institute; National Institute on Drug Abuse; National Institute of Mental Health; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES); Rectal cancer is a common disease with high mortality rates and limited therapeutic options. H...
The Long Non-Coding RNA SNHG12 as a Mediator of Carboplatin Resistance in Ovari...
Abildgaard, Cecilie; Do Canto, Luisa Matos; Rainho, Cláudia Aparecida [UNESP]; Marchi, Fabio Albuquerque; Calanca, Naiade [UNESP]; Waldstrøm, MarianneMade available in DSpace on 2022-05-01T15:46:19Z (GMT). No. of bitstreams: 0 Previous issue date: 2022-04-01; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES); Genetic and epigenetic changes contribute to intratumor heterogeneity and chemotherapy resistance in several tumor types. LncRNAs have been implicated, directly or indirectly, in the epigenetic regulation of gene expression. We investi...
Comprehensive analysis of DNA methylation and prediction of response to neoadju...
Canto, Luisa Matos Do; Barros-Filho, Mateus Camargo; Rainho, Cláudia Aparecida [UNESP]; Marinho, Diogo; Kupper, Bruna Elisa CatinMade available in DSpace on 2021-06-25T11:05:48Z (GMT). No. of bitstreams: 0 Previous issue date: 2020-11-01; Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); Universidade Estadual Paulista; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES); The treatment for locally advanced rectal carcinomas (LARC) is based on neoadjuvant chemoradiotherapy (nCRT) and surgery, which resul...
Germline mutation in MUS81 resulting in impaired protein stability is associate...
Rogatto, Silvia Regina
Increased DSG2 plasmatic levels identified by transcriptomic-based secretome an...
Cury, Sarah Santiloni [UNESP]; Lapa, Rainer Marco Lopez [UNESP]; de Mello, Julia Bette Homem; Marchi, Fábio AlbuquerqueMade available in DSpace on 2020-12-12T02:35:43Z (GMT). No. of bitstreams: 0 Previous issue date: 2020-04-01; Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Uddannelses- og Forskningsministeriet; Objectives: The tumor secretome deconvolution is a promising strategy to identify diagnostic and prognostic biomarkers. Here, transc...
The expression landscape of cachexia-inducing factors in human cancers
Freire, Paula Paccielli [UNESP]; Fernandez, Geysson Javier [UNESP]; de Moraes, Diogo [UNESP]; Cury, Sarah Santiloni [UNESP]Made available in DSpace on 2020-12-12T01:58:25Z (GMT). No. of bitstreams: 0 Previous issue date: 2020-08-01; Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); Background: Cachexia is a multifactorial syndrome highly associated with specific tumour types, but the causes of variation in cachexia prevalence and severity are unknown. While circulating plasma mediators (soluble cachectic factors...
Germline mutation in mus81 resulting in impaired protein stability is associate...
Pinheiro, Maisa [UNESP]; Lupinacci, Fernanda Cristina Sulla; Santiago, Karina Miranda; Drigo, Sandra Aparecida [UNESP]; Marchi, Fabio AlbuquerqueMade available in DSpace on 2020-12-12T02:08:56Z (GMT). No. of bitstreams: 0 Previous issue date: 2020-05-01; Syddansk Universitet; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES); Multiple primary thyroid cancer (TC) and breast cancer (BC) are commonly diagnos...