40 documents found, page 1 of 4
Comparative genomic hybridization detects novel amplifications in fibroadenomas...
Ojopi, Elida Paula Benquique [UNESP]; Rogatto, Silvia Regina [UNESP]; Caldeira, Jose Roberto Fiagro; Barbieri-Neto, Jose; Squire, Jeremy A.Made available in DSpace on 2022-04-28T19:55:19Z (GMT). No. of bitstreams: 0 Previous issue date: 2001-01-01; Comparative genomic hybridization analysis was performed for identification of chromosomal imbalances in 23 samples of fibroadenomas of the breast. Chromosomal gains rather than losses were a feature of these lesions. Only two cases with a familial and/or previous history of breast lesions had gain of 1...
H19-DMR allele-specific methylation analysis reveals epigenetic heterogeneity o...
Esteves, Leda Isabel De Castro Valente [UNESP]; Cervigne, Nilva De Karla [UNESP]; Javaroni, Afonso Do Carmo; Magrin, José; Kowalski, Luiz PauloMade available in DSpace on 2022-04-28T20:07:37Z (GMT). No. of bitstreams: 0 Previous issue date: 2006-02-01; Aberrant methylation of seven potential binding sites of the CTCF factor in the differentially methylated region upstream of the H19 gene (H19-DMR) has been suggested as critical for the regulation of IGF2 and H19 imprinted genes. In this study, we analyzed the allele-specific methylation pattern of CTC...
Twist1 and its genes' network are molecular signature for prediction of oral ca...
Silva, Sabrina Daniela; Alaoui-Jamali, Moulay A.; Soares, Fernando Augusto; Hier, Michael; Rogatto, Silvia Regina [UNESP]; Kowalski, Luiz PauloMade available in DSpace on 2020-12-10T22:01:02Z (GMT). No. of bitstreams: 0 Previous issue date: 2013-05-01; AC Camargo Hosp, Dept Head & Neck Surg & Otorhinolaryngol, Sao Paulo, Brazil; McGill Univ, Jewish Gen Hosp, Dept Oncol, Lady Davis Inst Med Res & Segal,Canc Ctr, Montreal, PQ H3T 1E2, Canada; McGill Univ, Jewish Gen Hosp, Dept Otolaryngol Head & Neck Surg, Montreal, PQ H3T 1E2, Canada; AC Camargo Hosp, ...
Integrated miRNA and mRNA expression analysis uncovers drug targets in laryngea...
Lapa, Rainer Marco Lopez [UNESP]; Barros-Filho, Mateus Camargo; Marchi, Fabio Albuquerque; Domingues, Maria Aparecida Custódio [UNESP]Made available in DSpace on 2019-10-06T16:27:20Z (GMT). No. of bitstreams: 0 Previous issue date: 2019-06-01; Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Objectives: The current treatment of laryngeal squamous cell carcinoma (LSCC)is based on radical surgery and radiotherapy resulting in high morbidity. Chemoradiotherapy ha...
High Diagnostic Accuracy Based on CLDN10, HMGA2, and LAMB3 Transcripts in Papil...
Barros-Filho, Mateus Camargo; Marchi, Fabio Albuquerque; Pinto, Clovis Antonio; Rogatto, Silvia Regina [UNESP]; Kowalski, Luiz PauloMade available in DSpace on 2018-11-27T00:48:00Z (GMT). No. of bitstreams: 0 Previous issue date: 2015-06-01; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); Context: Thyroid nodules are common in adult population and papillary thyroid carcinoma (PTC) is the most frequent malignant finding. The natural history of PTC remains po...
Integrated data analysis reveals potential drivers and pathways disrupted by DN...
Beltrami, Caroline Moraes; dos Reis, Mariana Bisarro [UNESP]; Barros-Filho, Mateus Camargo; Marchi, Fabio Albuquerque; Kuasne, Hellen [UNESP]Made available in DSpace on 2018-12-11T17:11:41Z (GMT). No. of bitstreams: 0 Previous issue date: 2017-05-02; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); Background: Papillary thyroid carcinoma (PTC) is a common endocrine neoplasm with a recent increase in incidence in many countries. Although PTC has been explored by gene ...
An Unexpectedly High Rate of Thrombophilia Disorders in Patients with Superfici...
Sobreira, Marcone Lima [UNESP]; Rogatto, Silvia Regina [UNESP]; dos Santos, Rodrigo Mattos [UNESP]; Santos, Izolete Thomazini [UNESP]Made available in DSpace on 2018-12-11T17:12:06Z (GMT). No. of bitstreams: 0 Previous issue date: 2017-01-01; Background Superficial vein thrombosis (SVT) is a common venous condition. Recent studies have shown that SVT is associated with high frequency of thromboembolic complications: from 22–37% for deep venous thrombosis and up to 33% for pulmonary embolism. Our goal was to assess the prevalence of major her...
Multidimensional integrative analysis uncovers driver candidates and biomarkers...
Marchi, Fabio Albuquerque; Martins, David Correa; Barros-Filho, Mateus Camargo; Kuasne, Hellen; Busso Lopes, Ariane Fidelis; Brentani, HelenaMade available in DSpace on 2018-12-11T17:13:40Z (GMT). No. of bitstreams: 0 Previous issue date: 2017-12-01; Molecular data generation and their combination in penile carcinomas (PeCa), a significant public health problem in poor and underdeveloped countries, remain virtually unexplored. An integrativemethodology combin ing genome-wide copy number alteration, DNA methylation, miRNA and mRNA expression analysis...
Genomic profile in gestational and non-gestational choriocarcinomas
Mello, Julia Bette Homem de; Ramos Cirilo, Priscila Daniele; Michelin, Odair Carlito [UNESP]; Custódio Domingues, Maria Aparecida [UNESP]Made available in DSpace on 2018-12-11T17:08:26Z (GMT). No. of bitstreams: 0 Previous issue date: 2017-02-01; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); Introduction Gestational (GC) (derived from the placenta) and non-gestational (NGC) choriocarcinomas are trophoblastic diseases originated from abnormal proliferation of t...
Association of UGT2B7, UGT1A9, ABCG2, and IL23R polymorphisms with rejection ri...
Cilião, Heloísa Lizotti; Camargo-Godoy, Rossana Batista Oliveira; de Souza, Marilesia Ferreira; dos Reis, Mariana Bisarro [UNESP]; Iastrenski, LorenaMade available in DSpace on 2018-12-11T17:32:31Z (GMT). No. of bitstreams: 0 Previous issue date: 2017-08-03; Despite advances in testing compatibility between donor and recipient, graft rejection remains a current concern. Single-nucleotide polymorphisms (SNPs) that codify altered enzymes of metabolism, drug transport, and the immune system may contribute to graft rejection in transplant patients. This study e...