Background: Nonsteroidal anti-inflammatory drugs (NSAIDs) are frequently avoided in mastocytosis, because of a potential increased risk for drug hypersensitivity reactions (DHRs) due to inhibition of cyclo-oxygenase (COX), subsequent depletion of prostaglandin E2 and release of leukotrienes. Objectives: Here, we aimed at determining the prevalence of mast cell (MC) mediator release symptoms triggered by NSAIDs ...
O Maciço Ibérico foi subdividido num conjunto de terrenos tectonoestra tigráficos com características próprias, entre os quais os Terrenos Finisterra (TF) e Ibérico (TI). O TF contacta com TI, nomeadamente com a Zonas Centro Ibérica e Ossa-Morena, através de uma zona de cisalhamento, a Zona de Cisalhamento Porto-Tomar-Ferreira do Alentejo. O TF apresenta características que contrastam com as que especializam o ...
The occurrence of a new tectono-stratigraphic terrane (Finisterra Terrane), located in the westernmost domains of the Porto-Tomar-Ferreira do Alentejo Shear Zone, has been highlighted in the last few years. Nevertheless, there are several gaps in the geological knowledge of this Terrane, including the interpretation of existing data in the framework of the new tectono-stratigraphic terrane proposal, with an ind...
Background: We aimed to perform the translation, cultural adaptation, and validation of the Pain Beliefs and Perceptions Inventory (PBPI) for the European Portuguese language and chronic pain population. Methods: This is a longitudinal multicenter validation study. A Portuguese version of the PBPI (PBPI-P) was created through a process of translation, back translation, and expert panel evaluation. The PBPI-P wa...
The acute tendinitis of the longus colli muscle is an unusual diagnosis in the cases of acute dysphagia with cervical pain. Is a self-limiting condition caused by abnormal calcium hydroxyapatite deposition in the prevertebral space and can cause pharyngeal swelling with impaired swallow. It is absolutely critical to make the differential diagnosis with deep cervical infections in order to avoid invasive treatme...
OBJECTIVES: There is a marked diversity in the reported success rates for achieving an intact tympanic membrane following tympanoplasty. Controversy exists about the factors thought to influence surgical outcome. These facts have important implications for the selection of patients who would benefit the most. This study reviews the factors thought to determine the anatomical and functional success of tympanopla...