6 documents found, page 1 of 1

Descriptive analysis of PD-L1 expression in non-small cell lung carcinoma biops...

Introduction: The expression of PD-L1 as a predictive marker of response to treatment of non-small cell lung cancer (NSCLC) allows the identification of patients most likely to benefit from treatment with inhibitors of immune checkpoints. The main objective of this study was to determine the PD-L1 positivity/negativity rates of biopsies diagnosed with NSCLC during the year 2017 and 2018 at CHUPorto and compare ...

Prognostic value of neutrophil/lymphocyte racio in palliative non-small cell lu...

Introduction: Immune checkpoint inhibitors (IC) are a new therapeutic option for non-small cell lung cancer. A higher neutrophil/lymphocyte ratio has been associated with worse outcomes in patients treated with immune checkpoint inhibitors, lung cancer included. Aim: Study the relation between value of neutrophil/lymphocyte ratio at day one (D1) and day 30 (D30) of treatment, and overall survival (OS) and progr...

Anemia de células falciformes: avaliação da hemoglobina fetal num grupo de cria...

IncX4 plasmid carrying the new mcr-1.9 gene variant in a CTX-M-8-producing Esch...

We studied a commensal colistin-resistant Escherichia coli isolated from a swine cecum sample collected at a slaughter, in Portugal. Antimicrobial susceptibility phenotype of E. coli LV23529 showed resistance to colistin at a minimum inhibitory concentration of 4 mg/L. Whole genome of E. coli LV23529 was sequenced using a MiSeq system and the assembled contigs were analyzed for the presence of antibiotic resist...

Molecular Epidemiology and Risk Factors of Carbapenemase-Producing Enterobacter...

In Portugal, the epidemiological stage for the spread of carbapenemase-producing Enterobacteriaceae (CPE) increased from sporadic isolates or single hospital clones (2010-2013), to hospital outbreaks, later. Here we report data from a 6-month study performed under the European Survey on Carbapenemase-Producing Enterobacteriaceae (EuSCAPE). During the study period, 67 isolates (61 Klebsiella pneumoniae and 6 Esc...

NDM-producing Enterobacteriaceae responsible for environmental contamination of...

Objective: The hospital environment plays a role in the cross-transmission of multidrug-resistant bacteria. The aim of this study was to identify potential carbapenemase-producing Enterobacteriaceae (CPE) reservoirs that might be responsible for a NDM-1 outbreak at a hospital in Portugal. Methods: An environmental investigation was instituted in a Portuguese hospital, after the occurrence of NDM-1-producing Pro...