69 documents found, page 1 of 7
Whole yeast cell synthesis of 5-hydroxymethylfurfural-derivatives from apple wa...
Martins, Cristiana; Costa, Carlos E.; Cunha, Joana Filipa Torres Pinheiro; Gullón, Beatriz; Romaní, Aloia; Domingues, LucíliaThe transition to renewable resources and bioprocesses is essential to address climate change and meet energy demands. Biorefineries offer a sustainable solution by valorising agro-industrial wastes, such as apple pomace, a by-product of the juice and cider industries. This study presents an efficient process to produce 5-hydroxymethylfurfural (HMF) derivatives using deep eutectic solvent (DES) and microwave-as...
Overview of resveratrol properties, applications, and advances in microbial pre...
Costa, Carlos E.; Romaní, Aloia; Domingues, LucíliaResveratrol is an antioxidant abundant in plants like grapes and peanuts and has garnered significant attention for its potential therapeutic applications. This review explores its chemical attributes, stability, and solubility, influencing its diverse applications and bioavailability. Resveratrols multifaceted therapeutic roles encompass: antioxidant, cardioprotective, anti-inflammatory, neuroprotective, anti-...
Production of HMF-derivatives from wine residues using Saccharomyces cerevisiae...
Cunha, Joana Filipa Torres Pinheiro; Romaní, Aloia; Domingues, LucíliaBackground There is an urgent need to develop bioprocesses independent of fossil resources to address resource depletion and mitigate environmental harm. Transitioning to a bio-based economy requires prioritizing chemical production processes that utilize renewable resources, ensuring sustainability and environmental responsibility. 5-Hydroxymethylfurfural (HMF) and its derivatives are promising building blocks...
Multi-feedstock biorefinery concept: Valorization of winery wastes by engineere...
Baptista, Sara Isabel Leite; Romaní, Aloia; Cunha, Joana T.; Domingues, LucíliaThe wine industry produces significant amounts of by-products and residues that are not properly managed, posing an environmental problem. Grape must surplus, vine shoots, and wine lees have the potential to be used as renewable resources for the production of energy and chemicals. Metabolic engineering efforts have established Saccharomyces cerevisiae as an efficient microbial cell factory for biorefineries. C...
Current options in the valorisation of vine pruning residue for the production ...
Jesus, Meirielly; Romaní, Aloia; Mata, Fernando; Domingues, LucíliaEurope is considered the largest producer of wine worldwide, showing a high market potential. Several wastes are generated at the different stages of the wine production process, namely, vine pruning, stalks, and grape marc. Typically, these residues are not used and are commonly discarded. Portugal generates annually approximately 178 thousand metric tons of wine production waste. In this context, the interest...
Biobased fuel and chemicals from lignocellulosic biomass: prospects and challenges
Pontes, Rita; Romaní, Aloia; Michelin, Michele; Domingues, Lucília; Nunes, João; Teixeira, J. A.The high world energy demand and climate changes have driven biofuels development through renewable sources. This chapter approaches the development of a process for the second-generation biofuels and chemicals production following a biorefinery scheme. First, it is presented the current status of biofuels worldwide, followed by a brief introduction regarding the biofuels of first (i.e., bioethanol, biodiesel, ...
Galactose to tagatose isomerization by the l-arabinose isomerase from Bacillus ...
Baptista, Sara Isabel Leite; Romaní, Aloia; Oliveira, Carla Cristina Marques de; Ferreira, Sara; Rocha, Cristina M.R.; Domingues, LucíliaTagatose is a rare sugar with increasing commercial interest as sweetener. Biotechnological production of d-tagatose by enzymatic isomerization of d-galactose provides an alternative to chemical processes. In the last years, l-arabinose isomerases (L-AIs) from different origins have been studied to increase the effectiveness of tagatose production. In this work, the L-AI from Bacillus subtilis, previously repor...
Cell surface engineering of Saccharomyces cerevisiae for simultaneous valorizat...
Cunha, Joana Filipa Torres Pinheiro; Gomes, Daniel G.; Romaní, Aloia; Inokuma, Kentaro; Hasunuma, Tomohisa; Kondo, Akihiko; Domingues, LucíliaThe viability of 2nd generation bioethanol processes is dependent on achieving high ethanol titers, which requires the use of high solid loadings that will negatively affect the fermentative microorganism besides increasing enzyme-associated costs. To solve this, and also problems of feedstock availability, lignocellulosic biomass can be mixed with dairy by-products to increase carbon content. In this study, in...
Integral valorization of Acacia dealbata wood in organic medium catalyzed by an...
Portela-Grandío, A.; Peleteiro, S.; Yáñez, R.; Romaní, AloiaIn this work, a novel delignification process was proposed for the fractionation of invasive species such as Acacia dealbata wood. Organosolv process catalyzed with an acidic ionic liquid, 1-butyl-3-methylimidazolium hydrosulfate was evaluated to obtain cellulose-enriched solids and liquid fractions rich in hemicelluloses derived compounds and lignin. Under selected operating conditions (190 °C, 60% ethanol, 60...
Multi-feedstock approach for ethanol production using cell surface engineered S...
Cunha, Joana Filipa Torres Pinheiro; Gomes, Daniel Gonçalves; Romaní, Aloia; Inokuma, Kentaro; Hasanuma, Tomohisa; Kondo, Akihiko; Domingues, LucíliaThe economic viability of second generation bioethanol has been pursued for several years, with struggles such as the high cost of enzymes and low ethanol titers receiving great attention. Saccharomyces cerevisiae is the preferred microorganism for bioethanol production and has been extensively studied and genetically modified for optimization of lignocellulosic processes. Moreover, S. cerevisiae strains isolat...