13 documents found, page 1 of 2
Development of a natural molluscicide prototype kit (MoluSchall) for the contro...
Paula-Andrade,Cynthia de; Coelho,Paulo Ricardo Silva; Nascimento,Ricardo Aurélio Pinto; Mota,Pedro Moacyr Pinto Coelho; Romano-Silva,Marco AurélioAbstract INTRODUCTION In Brazil, Biomphalaria glabrata, B. tenagophila, and B. straminea are intermediate hosts of Schistosoma mansoni, the etiological agent of schistosomiasis mansoni. Molluscicide use is recommended by the WHO for controlling the transmission of this parasite. Euphorbia milii latex has shown promising results as an alternative molluscicide. Thus, a natural molluscicide prototype kit based on ...
Lack of association between genetic polymorphism of FTO, AKT1 and AKTIP in chil...
Pereira,Patrícia de Araújo; Alvim-Soares Jr.,António Marcos; Sandrim,Valéria Cristina; Lanna,Carla Márcia Moreira; Souza-Costa,Débora CristineAbstract Objective: Obesity is a chronic disease caused by both environmental and genetic factors. Epidemiological studies have documented that increased energy intake and sedentary lifestyle, as well as a genetic contribution, are forces behind the obesity epidemic. Knowledge about the interaction between genetic and environmental components can facilitate the choice of the most effective and specific measures...
Doenças crônicas, cognição, declínio funcional e Índice de Charlson em idosos c...
Pimenta,Fausto Aloísio Pedrosa; Bicalho,Maria Aparecida Camargos; Romano-Silva,Marco Aurélio; Moraes,Edgar Nunes de; Rezende,Nilton Alves deOBJETIVO: Este estudo avaliou a associação entre as doenças crônico-degenerativas e o declínio funcional, a cognição e a predição da mortalidade. MÉTODOS: Um estudo transversal foi realizado em um Serviço de Geriatria em Belo Horizonte, Brasil, envolvendo 424 pacientes subdivididos em dois grupos: controle e com demência. Foram analisados dados sociodemográficos e ambientais, doenças crônicas degenerativas, o Í...
Relationship between neuropsychological and clinical aspects and suicide attemp...
Moraes,Paulo Henrique Paiva de; Neves,Fernando Silva; Vasconcelos,Alina Gomide; Lima,Isabela M. Magalhães; Brancaglion,Mayra; Sedyiama,Cristina YumiSome studies have investigated the possible relationship between suicide attempts and impulsivity in patients with bipolar disorder. The objective of this study was to assess the relationship between neuro-psychological and clinical aspects and suicide behavior in euthymic bipolar patients. The Iowa Gambling Task and the Conner's Continuous Performance Test evaluated impulsivity in 95 euthymic bipolar patients ...
Molecular medicine: a path towards a personalized medicine
Miranda,Debora Marques de; Mamede,Marcelo; Souza,Bruno Rezende de; Barros,Alexandre Guimarães de Almeida; Magno,Luiz Alexandre; Alvim-Soares Jr,AntônioPsychiatric disorders are among the most common human illnesses; still, the molecular and cellular mechanisms underlying their complex pathophysiology remain to be fully elucidated. Over the past 10 years, our group has been investigating the molecular abnormalities in major signaling pathways involved in psychiatric disorders. Recent evidences obtained by the Instituto Nacional de Ciência e Tecnologia de Medic...
Immunosenescence
Torres,Karen Cecília de Lima; Pereira,Patrícia de Araújo; Lima,Giselle Sabrina França de; Souza,Bruno Rezende; Miranda,Débora Marques de<p><b>INTRODUCTION:</b> Aging involves various complex cellular and molecular changes, including a general decline in immunological functions known as immunosenescence. The clinical consequences of immunosenescence include increased susceptibility to respiratory infections, neoplasias and cardiovascular diseases.<br> <b>OBJECTIVE:</b> To review the major cellular and molecular changes in immunosenescence.<br> <...
Associations between polymorphic variants of the tryptophan hydroxylase 2 gene ...
Rocha,Felipe Filardi da; Alvarenga,Nathália Bueno; Lage,Naira Vassalo; Romano-Silva,Marco Aurélio; Marco,Luiz Armando de; Corrêa,HumbertoOBJECTIVE: A substantial body of evidence suggests that obsessive-compulsive disorder has a genetic component, and substantial candidate genes for the disorder have been investigated through association analyses. A particular emphasis has been placed on genes related to the serotonergic system, which is likely to play an important role in the pathogenesis of obsessive-compulsive disorder. The gene for tryptopha...
Prejuízos no reconhecimento de emoções faciais em parentes de primeiro grau de ...
Neves,Maila de Castro Lourenço das; Tremeau,Fabien; Nicolato,Rodrigo; Lauar,Hélio; Romano-Silva,Marco Aurélio; Correa,HumbertoOBJETIVO: Diversos estudos sugerem que o processamento de emoções faciais está prejudicado em portadores de autismo e que tal prejuízo possa ser hereditário. Nós estudamos o reconhecimento de emoções faciais em parentes de primeiro grau de portadores de autismo e suas associações com o polimorfismo funcional de transportador de serotonina (5HTTLPR). MÉTODO: Foram avaliados 40 parentes de primeiro grau de portad...
A review of psychiatric genetics research in the Brazilian population
Cordeiro,Quirino; Souza,Bruno Rezende; Correa,Humberto; Guindalini,Camila; Hutz,Mara Helena; Vallada,Homero; Romano-Silva,Marco AurélioOBJECTIVE AND METHOD: A large increase in the number of Brazilian studies on psychiatric genetics has been observed in the 1970's since the first publications conducted by a group of researchers in Brazil. Here we reviewed the literature and evaluated the advantages and difficulties of psychiatric genetic studies in the Brazilian population. CONCLUSION: The Brazilian population is one of the most heterogeneous ...
Escala de Depressão Pós-natal de Edimburgo para triagem no sistema público de s...
Figueira,Patrícia; Corrêa,Humberto; Malloy-Diniz,Leandro; Romano-Silva,Marco AurélioOBJETIVO: Avaliar a utilização da Escala de Depressão Pós-natal de Edimburgo como instrumento de triagem no sistema público de saúde. MÉTODOS: A Escala foi administrada entre o 40º e 90º dia do pós-parto, a 245 mulheres que tiveram parto em uma maternidade privada no município de Belo Horizonte (MG), entre 2005 e 2006. As participantes foram submetidas a uma entrevista psiquiátrica estruturada (Mini-Plus 5.0) u...