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An intracellular metabolic signature as a potential donor-independent marker of...

Bispo, Daniela S. C.; Jesus, Catarina S. H.; Romek, Katarzyna; Marques, Inês M. C.; Oliveira, Mariana B.; Mano, João F.; Gil, Ana M.

This paper describes an untargeted NMR metabolomics study to identify potential intracellular donor-dependent and donor-independent metabolic markers of proliferation and osteogenic differentiation of human adipose mesenchymal stem cells (hAMSCs). The hAMSCs of two donors with distinct proliferating/osteogenic characteristics were fully characterized regarding their polar endometabolome during proliferation and...


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