6 documents found, page 1 of 1
Update on the role of Rifaximin in digestive diseases
Gasbarrini, Antonio; Ponziani, Francesca Romana; Ianiro, Gianluca; Trna, Jan; Tikhonov, Igor N.; Surdea-Blaga, Teodora; Neubauer, KatarzynaVarious environmental factors affecting the human microbiota may lead to gut microbial imbalance and to the development of pathologies. Alterations of gut microbiota have been firmly implicated in digestive diseases such as hepatic encephalopathy, irritable bowel syndrome and diverticular disease. However, while these three conditions may all be related to dysfunction of the gut-liver-brain axis, the precise pa...
The global NAFLD policy review and preparedness index: are countries ready to a...
Lazarus, Jeffrey V.; Mark, Henry E.; Villota-Rivas, Marcela; Palayew, Adam; Carrieri, Patrizia; Colombo, Massimo; Ekstedt, Mattias; Esmat, GamalBackground & aims: Non-alcoholic fatty liver disease (NAFLD) is a highly prevalent, yet largely underappreciated liver condition which is closely associated with obesity and metabolic disease. Despite affecting an estimated 1 in 4 adults globally, NAFLD is largely absent on national and global health agendas. Methods: We collected data from 102 countries, accounting for 86% of the world population, on NAFLD pol...
Defining comprehensive models of care for NAFLD
Lazarus, Jeffrey V.; Anstee, Quentin M.; Hagström, Hannes; Cusi, Kenneth; Cortez-Pinto, Helena; Mark, Henry E.; Roden, Michael; Tsochatzis, Emmanuel A.Non- alcoholic fatty liver disease (NAFLD) is now the leading cause of chronic liver disease globally. Despite the increased demand placed on health- care systems, little attention has been given to the design and implementation of efficient and effective models of care for patients with NAFLD. In many health- care settings, no formal pathways exist and, where pathways are in place, they are often not standardi...
Advancing the global public health agenda for NAFLD: a consensus statement
Lazarus, Jeffrey V.; Mark, Henry E.; Anstee, Quentin M.; Arab, Juan Pablo; Batterham, Rachel L.; Castera, Laurent; Cortez-Pinto, Helena; Crespo, JavierNon-alcoholic fatty liver disease (NAFLD) is a potentially serious liver disease that affects approximately one-quarter of the global adult population, causing a substantial burden of ill health with wide-ranging social and economic implications. It is a multisystem disease and is considered the hepatic component of metabolic syndrome. Unlike other highly prevalent conditions, NAFLD has received little attentio...
European ‘NAFLD Preparedness Index’ — Is Europe ready to meet the challenge of ...
Lazarus, Jeffrey V.; Palayew, Adam; Carrieri, Patrizia; Ekstedt, Mattias; Marchesini, Giulio; Novak, Katja; Ratziu, Vlad; Romero-Gómez, ManuelBackground & aims: Non-alcoholic fatty liver disease (NAFLD), which is closely associated with obesity, metabolic syndrome, and diabetes, is a highly prevalent emerging condition that can be optimally managed through a multidisciplinary patient-centred approach. National preparedness to address NAFLD is essential to ensure that health systems can deliver effective care. We present a NAFLD Preparedness Index for...
A cross-sectional study of the public health response to non-alcoholic fatty li...
Lazarus, Jeffrey V.; Ekstedt, Mattias; Marchesini, Giulio; Mullen, Jillian; Novak, Katja; Pericàs, Juan M.; Roel, Elena; Romero-Gómez, ManuelBackground & aims: Non-alcoholic fatty liver disease (NAFLD) is a growing public health problem worldwide and has become an important field of biomedical inquiry. We aimed to determine whether European countries have mounted an adequate public health response to NAFLD and non-alcoholic steatohepatitis (NASH). Methods: In 2018 and 2019, NAFLD experts in 29 European countries completed an English-language survey ...