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Global impact of the COVID-19 pandemic on stroke volumes and cerebrovascular ev...

Nguyen, Thanh N.; Qureshi, Muhammad M.; Klein, Piers; Yamagami, Hiroshi; Mikulik, Robert; Czlonkowska, Anna; Abdalkader, Mohamad; Sedova, Petra

Background and objectives: Declines in stroke admission, IV thrombolysis (IVT), and mechanical thrombectomy volumes were reported during the first wave of the COVID-19 pandemic. There is a paucity of data on the longer-term effect of the pandemic on stroke volumes over the course of a year and through the second wave of the pandemic. We sought to measure the effect of the COVID-19 pandemic on the volumes of str...


Outcomes of cerebral venous thrombosis due to vaccine-induced immune thrombotic...

van de Munckhof, Anita; Lindgren, Erik; Kleinig, Timothy J.; Field, Thalia S.; Cordonnier, Charlotte; Krzywicka, Katarzyna; Poli, Sven

Background: Cerebral venous thrombosis (CVT) due to vaccine-induced immune thrombotic thrombocytopenia (VITT) is a severe condition, with high in-hospital mortality rates. Here, we report clinical outcomes of patients with CVT-VITT after SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) vaccination who survived initial hospitalization. Methods: We used data from an international registry of patients ...


Prioritization process for European Academy of Neurology clinical practice guid...

Aleksovska, Katina; Bassetti, Claudio L. A.; Berger, Thomas; Carvalho, Vanessa; Costa, João; Deuschl, Günther; Frederiksen, Kristian S.; Jaarsma, Joke

Background and purpose: The development of high-quality clinical practice guidelines (CPGs) takes substantial time, effort, and resources. During the past years, the European Academy of Neurology (EAN) guideline production was significantly increased, so the need to develop clear, transparent, and methodologically solid criteria for prioritizing guideline topics became apparent. With this paper, we aim to defin...


Guidelines should be guidelines: time to leave the terms "consensus" and "posit...

Aleksovska, Katina; Bassetti, Claudio L. A.; Berger, Thomas; Carvalho, Vanessa; Costa, João; Deuschl, Günther; Frederiksen, Kristian Steen

Clinical guidelines are “statements that include recommendations, intended to optimize patient care, that are informed by a systematic review of evidence and an assessment of the benefits and harms of alternative care options”. Clinical guidelines are increasingly becoming a part of neurology clinical practice, most probably because they may improve patient clinical outcomes. Methods and strategies intended to ...


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