6 documents found, page 1 of 1
Endocan as a marker of endotheliitis in COVID-19 patients: modulation by veno-v...
Reina-Couto, M; Alves, D; Silva-Pereira, C; Pereira-Terra, P; Martins, S; Bessa, J; Teixeira-Santos, L; Pinho, D; Morato, M; Dias, CC; Sarmento, A"Background and aims: Endocan has been scarcely explored in COVID-19, especially regarding its modulation by veno-venous extracorporeal membrane oxygenation (VV-ECMO), hypertension or previous renin-angiotensin-aldosterone system (RAAS) inhibitors treatment. We compared endocan and other endotheliitis markers in hospitalized COVID-19 patients and assessed their modulation by VV-ECMO, hypertension and previous R...
Evaluation of urinary cysteinyl leukotrienes as biomarkers of severity and puta...
Reina-Couto, M; Roboredo-Madeira, M; Pereira-Terra, P; Silva-Pereira, C; Martins, S; Teixeira-Santos, L; Pinho, D; Dias, A; Cordeiro, G; Dias, CCBackground Cysteinyl leukotrienes (CysLT) are potent inflammation-promoting mediators, but remain scarcely explored in COVID-19. We evaluated urinary CysLT (U-CysLT) relationship with disease severity and their usefulness for prognostication in hospitalized COVID-19 patients. The impact on U-CysLT of veno-venous extracorporeal membrane oxygenation (VV-ECMO) and of comorbidities such as hypertension and obesity ...
Proinflammatory and endothelial activation profiles in hospitalized COVID-19 pa...
Silva-Pereira, PDC; Reina-Couto, M; Alves, D; Pereira-Terra, P; Martins, S; Bessa, J; Teixeira-Santos, L; Pinho, D; Morato, M; Sarmento, A; Tavares, Mn/a
Risk Factors for Mortality in Patients With COVID-19 Needing Extracorporeal Res...
Riera, J; Alcántara, S; Bonilla, C; Fortuna, P; Blandino Ortiz, A; Vaz, A; Albacete, C; Millán, P; Ricart, P; Boado, MV; Ruiz de Gopegui, PWhen indicating ECMO in patients with COVID-19, centre case volume, age, driving pressure and the duration of symptoms (not the length of MV) should be taken into account. Large drainage cannula and high PEEP levels during the first days are recommended.
Urinary Cysteinyl Leukotrienes as Biomarkers of Endothelial Activation, Inflamm...
Reina-Couto, M; Santos-Oliveira, M; Pereira-Terra, P; Silva-Pereira, C; Quelhas-Santos, J; Duarte, Á; Martins, S; Serrão, P; Dias, CC; Morato, MCysteinyl leukotrienes (CysLT) are potent vascular leakage-promoting agents but have been scarcely explored in human septic shock (SS). We evaluated CysLT at admission and during hospitalization and their correlation with endothelial dysfunction, inflammation, oxidative stress, the renin–angiotensin–aldosterone system, and cardiac, renal, respiratory, and hepatic parameters in SS patients. Blood and spot-urine ...
Non-invasive hemodynamic evaluation by Doppler echocardiography
Gaspar, A; Azevedo, P; Roncon-Albuquerque, RThe approach for treating a hemodynamically unstable patient remains a diagnostic and therapeutic challenge. Stabilization of the patient should be rapid and effective, but there is not much room for error. This narrow window of intervention makes it necessary to use rapid and accurate hemodynamic evaluation methods. Echocardiography is the method of choice for the bedside evaluation of patients in circulatory ...