Objective: To present cases of ptosis in HIV-1 patients on long-term antiretroviral therapy (ART) and review the existing literature. Methods: Five HIV-1-positive patients with slowly progressive bilateral ptosis underwent a comprehensive diagnostic evaluation, including imaging studies, neurophysiological testing, muscle biopsy, and genetic analysis. A literature review was conducted. Results: On clinical exam...
Endometrial adenocarcinoma is one of the most frequent malignant neoplasms of the female genital tract in Western Europe and North America. More than 90% of cases occur in women over 50 years-old, however, 4% of cases occur before 40 years-old. The present clinical case concerns a 74 years-old woman with blood loss, a vaginal ulcerated lesion, and an enlarged uterus. She consequently underwent a colpocytology, ...
Adenoid cystic carcinoma in Bartholin’s gland is a rare malignant gynecologic tumor that appears as a solid lesion, movable and painful, with slow growth. It is a tumor associated with frequent local recurrence and metastasis, which can occur several years after the primary lesion. The clinical diagnosis includes cystic lesion or abscess. However, it has a very particular morphologic presentation, which allows ...
Introduction: Diagnostic yield of brain biopsy in neoplastic brain disease is high and its clinical impact is well established. In nonneoplastic brain disease with negative conventional investigation, decision to undergo invasive procedures is difficult due to its inherent risk and known lower diagnostic yield. Research question: What is the clinical impact of brain biopsy results on management of nonneoplastic...
A ocorrência simultânea de duas neoplasias malignas primárias é uma condição pouco frequente, predisposta por fatores ambientais e genéticos. Descrevemos o caso clínico de uma mulher de 50 anos, fumadora, com diagnóstico de linfoma linfocítico/ leucemia linfocítica crónica (LLC). Após a deteção de um nódulo no lobo superior do pulmão direito e de múltiplas adenopatias mediastínicas, foi efetuada broncofibroscop...
Os quistos do mesentério são tumores intra-abdominais benignos raros. Podem manifestar-se em qualquer faixa etária, no entanto, cerca de 33% manifestam-se em crianças com menos de 15 anos. Na maioria dos casos são assintomáticos e o seu diagnóstico, frequentemente, é um achado incidental. Embora a etiologia dos quistos seja desconhecida, várias são as teorias propostas para explicar a sua formação. O tratamento...
INTRODUCTION: Predicting outcome in comatose survivors of cardiac arrest is based on data validated by guidelines that were established before the era of therapeutic hypothermia. We sought to evaluate the predictive value of clinical, electrophysiological and imaging data on patients submitted to therapeutic hypothermia. MATERIALS AND METHODS: A retrospective analysis of consecutive patients receiving therapeut...
BACKGROUND AND PURPOSE: The influence of apolipoprotein E (ApoE) polymorphism on clinical severity of multiple sclerosis (MS) is still controversial. Cigarette smoking has been suggested to influence the progression of disability in these patients. In this study, we aimed to investigate whether an interaction of smoking with the ApoE polymorphism influences the progression of disability in MS patients. METHODS:...