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Enzymatic degradation of ochratoxin A: the role of ultra-pure water

Santos, Joana; Oliveira, Constança; Teixeira, Filipe; Venâncio, Armando; Silva, C.

Ochratoxin A (OTA) is a toxic mycotoxin, making its removal from food essential for public health. This study examines OTA degradation by porcine pancreatic lipase (PPL) in ultra-pure water versus buffer systems through in vitro assays and molecular modeling. The results show that PPL fully degrades OTA in ultra-pure water within 7 h at 44 °C, whereas only partial degradation occurs in phosphate buffer. After 4...


Exploring canine mast cell tumors: An investigation into demographic characteri...

Catarino, José; Pinello, Katia; Niza-Ribeiro, João; Santos, Joana; Payan-Carreira, Rita; Reis, Joana; Faísca, Pedro

Mast cell tumors (MCT) are among the most common neoplasia in dogs, representing up to 21 % of skin tumors. However, etiology and risk factors for its development remain unclear. This study aimed to reduce this knowledge gap by comprehensively analyzing 905 MCT cases diagnosed in Portugal between 2019 and 2021, using descriptive and inferential analyses. Most tumors affected the skin, with 69.9 % and 21.2 % cla...


Self‐management in children and adolescents with chronic illness: an evolutiona...

Catarino, Marta; Macedo, Lúcia; Santos, Joana; Charepe, Zaida; Festas, Constança

Aim: To increase conceptual clarity regarding the self-management of school-age children and adolescents with chronic illnesses in a community context. Design: Concept Analysis: Rodgers' evolutionary approach. Data Sources: Search conducted in the Cumulative Index to Nursing and Allied Health Literature, Psychology and Behavioural Sciences Collection, Nursing and Allied Health Collection, Academic Search Comple...


NADES-in-Oil Emulsions Enriched with Essential Oils for Cosmetic Application

Freitas, David; Rocha, Diana; Santos, Joana; Noro, Jennifer Martins; Tavares, Tânia D.; Teixeira, Marta O.; Araújo, Daniela; Castro, Joana Isabel Reis

The following supporting information can be downloaded at: https://www.mdpi.com/article/10.3390/pr13020374/s1, Figure S1: TGA degradation steps (a) and TGA thermograms (b) and c) of all the produced TEs.; Table S1: Compounds identified in olive oil by GC-MS.; Table S2: Compounds identified in thyme oil by GC-MS.; Table S3: Compounds identified in oregano oil by GC-MS.; Table S4: Evaluation of the inhibition of ...


Laccase-catalyzed polymerized natural bioactives for enhanced mushroom tyrosina...

Costa, Diana; Rocha, Diana; Santos, Joana; Noro, Jennifer Martins; Ribeiro, Artur; Silva, Carla

Skin hyperpigmentation disorders, such as melasma, are linked to excessive melanin production, primarily regulated by the enzyme tyrosinase (TYR). While current inhibitors like kojic acid (KA) are effective, they often cause adverse side effects, driving the search for safer andnatural alternatives. This study evaluated the TYR inhibitory potential of bioactive-rich extracts from acorn, cocoa, cork, and eucalyp...


Empirical evidence for the validity of the Job Crafting Scale (JCS) in a Portug...

Viseu, João; Santos, Joana; Semedo, Carla; Bakker, Arnold B.; Tims, Maria; Agrela, Sara; Lagareiro, Beatriz

Purpose – This study aims to adapt and validate the Job Crafting Scale (JCS), a measure based on the conceptualization of job crafting of the job demands–resources theory, for a sample of Portuguese workers and to test its psychometric properties regarding validity (factor, convergent, discriminant, and criterion) and reliability. Design/methodology/approach – Two subsamples (n1 ¼ 315 and n2 ¼ 329) of Portugues...


Inventário de Felicidade no Trabalho (IFT) – Análise fatorial para a construção...

Ribeiro, Andresa; Jesus, Saúl Neves; Viseu, João; Silva, Narbal; Santos, Joana

O trabalho se caracteriza como uma categoria central da vida humana. Isto faz refletir sobre a importância de se mensurar quais os fatores contribuem para a construção de ambientes laborais saudáveis e felizes com base na Psicologia Positiva. O estado psicológico de felicidade é socialmente construído, composto por bases hedônicas e eudaimônicas interconectadas, o que promove emoções e sentimentos preponderan...


Blue Thinking. Notes on an advanced training programme for the enhancement of w...

Cardoso, Ana; Santos, Joana; Bártolo, José; Simão, José; Simões, José; Vilar, Maria

Blue Thinking is the concept and methodology behind the Blue Design Alliance. A new advanced higher education programme focused on the enhancement of water, ocean and river resources, as well as social and environmental sustainability through the application of design tools and methodologies. ESAD - Escola Superior de Artes e Design is promoting the Blue Design Alliance - an alliance between four higher educati...


Establishment of local diagnostic reference levels for abdomen and chest radiog...

Arriaga, A.; Gonçalves, Cláudia; Teles, P.; Santos, Joana; Simãozinho, Paula; Sousa-Santos, Patrick Emanuell Mesquita

Purpose: To assess doses variabilities in the same abdomen and chest RX exams for adults, to check the need for dose harmonization. To calculate Diagnostic Reference Levels (DRL), mandatory in the European Union, for the Algarve district in Portugal. Our results can be a valuable reference for the Portuguese official determination of DRLs, still in progress.Method: We considered 4,936 abdomen and 41,320 chest r...


Empirical evidence for the validity of the job crafting scale (JCS) in a Portug...

Viseu, João; Santos, Joana; Semedo, Carla Santarém; Bakker, Arnold B.; Tims, Maria; Agrela, Sara; Lagareiro, Beatriz

Purpose - This study aims to adapt and validate the Job Crafting Scale (JCS), a measure based on the conceptualization of job crafting of the job demands-resources theory, for a sample of Portuguese workers and to test its psychometric properties regarding validity (factor, convergent, discriminant, and criterion) and reliability. Design/methodology/approach - Two subsamples (n1 = 315 and n2 = 329) of Portugues...


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