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Supercritical CO2 technology: the next standard sterilization technique?
Soares, Gonçalo C.; Learmonth, David A.; Vallejo, Mariana C.; Davila, Sara Perez; González, Pío; Sousa, Rui A.; Oliveira, Ana L.Sterilization of implantable medical devices is of most importance to avoid surgery related complications such as infection and rejection. Advances in biotechnology fields, such as tissue engineering, have led to the development of more sophisticated and complex biomedical devices that are often composed of natural biomaterials. This complexity poses a challenge to current sterilization techniques which frequen...
A new era for sterilization based on supercritical CO2 technology
Ribeiro, Nilza; Soares, Gonçalo C.; Santos-Rosales, Víctor; Concheiro, Angel; Alvarez-Lorenzo, Carmen; García-González, Carlos A.; Oliveira, Ana L.The increasing complexity in morphology and composition of modern biomedical materials (e.g., soft and hard biological tissues, synthetic and natural‐based scaffolds, technical textiles) and the high sensitivity to the processing environment requires the development of innovative but benign technologies for processing and treatment. This scenario is particularly applicable where current conventional techniques ...
New insights on biopolymer sterilization using supercritical co2 technology
Soares, Gonçalo C.; Silva, Miguel; Borges, Sandra; Baptista-Silva, Sara; Freixo, Ricardo; Learmonth, David A.; Oliveira, Ana L.