14 documents found, page 1 of 2

Cutting-edge hybrid dressings: combining silk medical textiles and decellulariz...

Aim: Burns affect 11 million people globally each year, with 180,000 fatalities [1]. This study investigates a multilayer burn dressing combining silk fibroin (SF) fabric with highly- preserved decellularized porcine small intestine (dPSI) to support tissue regeneration and wound integration [2]. A silk sericin (SS) hydrogel is included as interface for structural integrity and anti-inflammatory benefits, enhan...

Development of a decellularized extracelular matrix from porcine aorta for hear...

Cardiovascular diseases are the leading cause of adult mortality worldwide, according to the World Health Organization [1]. An important surgical approach for treating diseased aortic valves is the Ross procedure, in whic the affected aortic valve is replaced with an autograft from the patient’s own pulmonary valve.

Biohybrid dressings: integrating silk fibroin textiles with decellularized biol...

Burns affect 11 million people globally each year with 180,000 associated fatalities. This study proposes a multilayer hybrid dressing combining a silk fibroin (SF) textile with decellularized porcine small intestine (dPSI) capable of simultaneously provide wound protection and tissue regeneration. A silk sericin (SS) hydrogel was embedded into the decellularized tissue ensuring the integration with the textile...

Development of a decellularized extracelular matrix from porcine aorta for hear...

Cardiovascular diseases are the leading cause of adult mortality worldwide, according to the WHO [1]. An important surgical approach for treating diseased aortic valves is the Ross procedure, in which the affected aortic valve is replaced with an autograft from the patient’s own pulmonary valve. The main concern about this procedure is linked to wall dilatation, which can lead to valve leakage and reoperation. ...

Exploring rabbit skin as a novel decellularized dermal substitute for burn woun...

Aim: Burn wounds represent a significant medical challenge. Autografts remain the standard treatment, however, are unsuitable for deep or extensive burns(1). Decellularized skin xenografts offer a viable alternative, having significantly reduced immunogenicity, still there is currently no skin-derived decellularized xenografic matrix due to its low resemblance to human skin (2)(3). This study proposes decellula...

Biohybrid solutions for burn care: merging silk medical textiles with decellula...

Is decellularized rabbit dermis a viable option for skin wound healing and rege...

Burn wounds remain a significant challenge in medical care, requiring effective wound coverage to restore the skin barrier and promote healing or support skin reconstruction. The use of autologous grafts as substitutes is still the standard treatment, however, it is not suitable for deep and extensive burns (1). Decellularized skin allografts and xenografts have emerged as suitable options, using decellularizat...

Biohybrid solutions for burn care: merging silk medical textiles with decellula...

Is decellularized rabbit dermis a viable option for skin wound healing and rege...

Burn wounds remain a major clinical challenge, requiring effective coverage to restore the skin barrier and support healing. Autologous grafts are the standard treatment but are limited in deep or extensive burns [1]. Decellularized allografts and xenografts offer alternatives by removing immunogenic material while preserving ECM components [2]. Considering that xenografts source availability is significantly h...

Integrating decellularized small intestine matrices and silk-based textiles for...

Medical textiles are frequently utilized in implants and other medical devices. But even though they are successful in providing structural support for the transplanted organs, they typically exhibit an inert nature that hinders the tissues' or organs' ability to repair or regenerate (1). Decellularized biological tissues, on the other hand, have a remarkable biological character because they include all the na...