2 documents found, page 1 of 1
Topical caffeine delivery using biocellulose membranes: a potential innovative ...
Silva, Nuno H. C. S.; Drumond, Ines; Almeida, Isabel F.; Costa, Paulo; Rosado, Catarina F.; Neto, Carlos Pascoal; Freire, Carmen S. R.In this study, biocellulose (BC) membranes have been investigated as caffeine topical delivery systems, for the potential treatment of cellulite. BC-caffeine membranes were prepared by a simple approach and the permeation of caffeine through human epidermis, from BC or from conventional formulation systems (solution and gel), was compared in vitro to assess their therapeutic applicability. Diffusion studies wit...
Biocellulose Membranes as Supports for Dermal Release of Lidocaine
Trovatti, Eliane; Silva, Nuno H. C. S.; Duarte, Iola F.; Rosado, Catarina F.; Almeida, Isabel F.; Costa, Paulo; Freire, Carmen S. R.Biocellulose (BC) is a highly pure form of cellulose, produced in the form of a swollen membrane, with several applications in the biomedical area. In this study, the behavior of BC membranes as systems for topical delivery of lidocaine was evaluated. The BC-lidocaine membranes were prepared and characterized in terms of structural and morphological properties. A uniform distribution of the drug inside the BC m...