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iHandU: A Novel Quantitative Wrist Rigidity Evaluation Device for Deep Brain St...

Lopes, EM; Vilas-Boas, MC; Dias, D; Rosas, MJ; Vaz, R; Cunha, JP

Deep brain stimulation (DBS) surgery is the gold standard therapeutic intervention in Parkinson's disease (PD) with motor complications, notwithstanding drug therapy. In the intraoperative evaluation of DBS's efficacy, neurologists impose a passive wrist flexion movement and qualitatively describe the perceived decrease in rigidity under different stimulation parameters and electrode positions. To tackle this s...

Date: 2020   |   Origin: Saúde - CUF

Long-term mortality analysis in Parkinson's disease treated with deep brain sti...

Rocha, S; Monteiro, A; Linhares, P; Chamadoira, C; Bastos, MA; Reis, C; Sousa, C; Lima, J; Rosas, MJ

Background. Few data have been published regarding long-term mortality in patients with Parkinson's disease treated with DBS. Methods. This study analyzed long-term mortality rates, causes, and correlates in PD patients treated with DBS. Results. 184 consecutive patients were included; mean follow-up was 50 months. Fifteen deaths occurred (total 8.15%, annual mortality rate 1.94%). Mean age at disease onset and...


Late-onset Lennox-Gastaut syndrome as a phenotype of 15q11.1q13.3 duplication

Rocha, J; Guerra, C; Oliveira, R; Dória, S; Rego, R; Rosas, MJ

The clinical symptoms associated with chromosome 15q duplication syndrome manifest through a heterogeneous group of symptoms characterised by hypotonia, delay in motor skills and language development, cognitive and learning disabilities, autism spectrum disorder and refractory epilepsy. The late development of Lennox-Gastaut syndrome in patients with 15q11q13 duplication is a possibility that physicians should ...


Delay in hospital admission of patients with cerebral vein and dural sinus thro...

Ferro, JM; Lopes, MG; Rosas, MJ; Fontes, J; VENOPORT Investigators

Factors influencing early hospital admission have been described for several stroke types but not for cerebral vein and dural sinus thrombosis (CVT). CVT is more difficult to diagnose than arterial stroke; delay in hospital admission may postpone CVT treatment. The purposes of this study were: (1) to describe the delay between the onset of symptoms and hospital admission of patients with CVT, and (2) to identif...


Diagnosis of stroke by the nonneurologist: a validation study.

Ferro, J; Pinto, A; Falcão, I; Rodrigues, G; Ferreira, J; Falcão, F; Azevedo, E; Canhão, P; Melo, T; Rosas, MJ; Oliveira, V; Salgado, AV

BACKGROUND AND PURPOSE: The first medical contact of an acute stroke victim is often a nonneurologist. Validation of stroke diagnosis made by these medical doctors is poorly known. The present study seeks to validate the stroke diagnoses made by general practitioners (GPs) and hospital emergency service physicians (ESPs). METHODS: Validation through direct interview and examination by a neurologist was performe...


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