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Increasing the fungicidal action of Amphotericin B by inhibiting the Nitric Oxi...

Vriens,Kim; Kumar, Phalguni Tewari; Struyfs, Caroline; Cools, Tanne L.; Spincemaille, Pieter; Kokalj, Tadej; Marques, Belém Sampaio; Ludovico, Paula

Amphotericin B (AmB) induces oxidative and nitrosative stresses, characterized by production of reactive oxygen and nitrogen species, in fungi. Yet, how these toxic species contribute to AmB-induced fungal cell death is unclear. We investigated the role of superoxide and nitric oxide radicals in AmB's fungicidal activity in Saccharomyces cerevisiae, using a digital microfluidic platform, which enabled monitorin...


X-ray computed (micro) tomography for detecting internal defects in fruit

Verboven, Pieter; Tri Ho, Quang; Herremans, Els; Lammertyn, Jeroen; Nicolaï, Bart

Internal disorders in horticultural products are not revealed by external visual symptoms. Non-destructive and non-invasive monitoring techniques are required to detect the occurrence and investigate development of internal disorders. X-ray CT allows visualization and analysis of plant materials with a resolution down to a few micrometers, and without sample preparation or chemical fixation. X-ray tomography is...


Electronic tongue as a screening tool for rapid analysis of beer

Polshin, Evgeny; Rudnitskaya, Alisa; Kirsanov, Dmitriy; Legin, Andrey; Saison, Daan; Delvaux, Filip; Delvaux, Freddy R.; Nicolaï, Bart M.

An electronic tongue (ET) comprising 18 potentiometric chemical sensors was applied to the quantitative analysis of beer. Fifty Belgian and Dutch beers of different types were measured using the ET. The same samples were analyzed using conventional analytical techniques with respect to the main physicochemical parameters. Only non-correlated physicochemical parameters were retained for further analysis, which w...


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