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Environmental impact and costs of a switching program of intravenous to subcuta...

Oliveira, R.; Roseira, J.; Araújo, N.; Cavaco, C.; André, J.; Sousa, M.; Sousa, H. Tavares de; Cunha, M.

We aimed to compare real-life direct and indirect costs and the environmental impact of switching IBD patients from IV to SC infliximab (IFX).


Predicting outcomes of disease in patients with primary sclerosing cholangitis ...

Oliveira, R.; Viegas, M. I.; Abrantes, D.; Conde, P. Vaz; Saraiva, M.; Espinheira, M. D. C.; Trindade, E.; Carvalho, I.; Perdigoto, D.

The impact of coexistent IBD and PSC on disease progression and prognosis is unclear. This study evaluates outcomes in patients with both conditions, using the novel PSC Risk Estimate Tool (PREsTO) for PSC prognosis.


Vitamin and micronutrient excess in patients with Crohn’s disease under oral am...

Oliveira, R.; Mendes, B.; Neves, J. Cunha; Amorim, E.; Roseira, J.; Sousa, H. Tavares de

Exclusive enteral nutrition (EEN) is recommended for preoperative nutritional optimization (PNO) in adult Crohn's disease (CD) patients. However, during ambulatory oral EEN, a lack of routine monitoring for vitamins may occur, with a potential risk of hypervitaminosisrelated toxicity, which remains unexplored. This study aims to assess the serum levels of vitamins and micronutrients in CD patients undergoing EE...


Serum neutrophil biomarkers to predict crohn's disease progression and inflixim...

Magalhaes, D.; Santiago, M.; Patita, M.; Arroja, B.; Lago, P.; Rosa, I.; Sousa, Helena Tavares; Ministro, P.; Mocanu, I.; Vieira, A.; Castela, J.

Background and aims: Predicting the treatment outcomes of biological therapies is an unmet need in Crohn's Disease. In this study, we explored the potential of serum neutrophil-related biomarkers to predict infliximab therapeutic results and disease progression in Crohn's Disease patients, over a 2-year period, in a real-world setting. Methods: The study included 100 asymptomatic Crohn's Disease patients in the...


Characterization of Clostridioides strains and antibiotic resistance profile in...

Oliveira, R.; Sousa, H. Tavares de; Roseira, J.

There is an increasing incidence of community-acquired Clostridioides difficile infection (CDI), particularly in IBD. Due to a suspected community outbreak in mid-2023, we aimed to investigate the microbiological and antibiotic resistance profile of CDI in an IBD cohort, employing blind central reading, in order to better understand its epidemiology.


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