24 documents found, page 1 of 3
Green surgery: a systematic review of the environmental impact of laparotomy, l...
Cunha, Miguel F.; Neves, João Cunha; Roseira, Joana; Pellino, Gianluca; Castelo-Branco, PedroSurgery is the most energy-intensive healthcare sector, but data on the environmental impact of abdominal surgical techniques are limited. This systematic review aims to identify the most sustainable approach among open, laparoscopic, and robotic surgeries. We searched MEDLINE, Cochrane, and Web of Science databases (inception to March 2024) for studies on the carbon footprint of abdominal surgery, focusing on ...
Clinical significance of histologic healing in IBD: evidence from randomized co...
Estevinho, Maria Manuela; Roseira, Joana; Teixeira, Pedro Vilela; Dignass, Axel; Magro, FernandoHistologic mucosal healing (HMH) has emerged as a crucial target in managing inflammatory bowel disease, complementing the established goal of endoscopic mucosal healing. This review evaluates the significance of HMH in both Crohn's disease (CD) and ulcerative colitis (UC). In UC, strong evidence shows that HMH correlates with improved long-term outcomes, including reduced hospitalization rates, and decreased n...
Endoscopy‐related musculoskeletal injuries: a systematic review and meta‐analys...
de Oliveira, Raquel; Roseira, Joana; Estevinho, Maria Manuela; Sousa, Helena Tavares; Rolanda, Carla; Meining, Alexander; Walter, BenjaminBackgroundEndoscopy-related musculoskeletal injuries (ERIs) are a major occupational hazard, impacting career longevity and personal well-being.ObjectiveThis systematic review and meta-analysis aimed to update and expand on previous findings by assessing prevalence, risk factors and management of ERIs among endoscopists.MethodsFollowing PRISMA guidelines, we systematically searched MEDLINE, Web of Science and S...
Thiopurines have no impact on outcomes of Crohn's disease patients beyond 12 mo...
Sousa, Paula; Patita, Marta; Arroja, Bruno; Lago, Paula; Rosa, Isadora; Sousa, Helena Tavares; Ministro, Paula; Mocanu, Irina; Vieira, AnaThe emergence of new treatments the inflammatory bowel diseases (IBD) raised questions regarding the role of older agents, namely thiopurines. Aims: To clarify the benefits of combination treatment with thiopurines on Crohn's disease (CD) patients in the maintenance phase of infliximab. Methods: In this analysis of the 2 -year prospective multicentric DIRECT study, patients were assessed in terms of clinical ac...
Vedolizumab and new‐onset spondyloarthritis: debunking the myth
Roseira, Joana; Marafini, Irene; Noor, Nurulamin M.Despite an increased understanding of the etiopathogenesis of Inflammatory Bowel Disease (IBD), prevention or cure remains a distant aspiration and current treatment approaches often do not achieve long‐term disease remission. An additional complexity is that IBD can also be associated with a range of extra‐intestinal manifestations (EIMs). Among these EIMs, peripheral and axial rheumatological manifestations a...
Food-related quality of life and its predictors in inflammatory bowel disease
Oliveira, Raquel; Martins, Viviana; Sousa, Helena Tavares; Roseira, JoanaBackground Inflammatory bowel disease (IBD) is associated with dietary restrictions and food- and drink-driven daily life limitations. Food-related quality of life (FR-QoL) is still an under-addressed issue in IBD. Aim We aimed to study determinants of FR-QoL in an IBD cohort, namely objective measures of disease activity. Methods A cross-sectional case-control study was conducted in a Tertiary Hospital, includ...
Food-related quality of life in inflammatory bowel disease: translation and val...
Oliveira, Raquel; Martins, Viviana Maria Varajão; Teixeira, Laetitia; Sousa, Helena Tavares; Roseira, JoanaFood-related quality of life (FR-QoL) has been shown to be an important patient-reported outcome in inflammatory bowel disease (IBD). We aimed to translate and validate a Portuguese version of the FR-QoL-29. Methods: This was a case-control cross-sectional study undertaken at a tertiary hospital. After obtaining the original authors' authorization, both forward and backward translations of the original FR-QoL-2...
Treatment options for refractory ulcerative colitis: Small molecules, big effects
Marafini, Irene; Roseira, Joana; Duijvestein, MarjolijnAlthough the majority of patients with ulcerative colitis (UC) have a mild-to-moderate disease, approximately 10%–15% experience a severe disease course and require immunosuppressive therapies.1 A better understanding of the mechanisms sustaining the pathogenic process in inflammatory bowel diseases (IBD) has largely contributed to expand the therapeutic armamentarium for this group of patients. Alongside with ...
How many biomarker measurements are needed to predict prognosis in Crohn's dise...
Magro, Fernando; Estevinho, Maria Manuela; Catalano, Gaia; Patita, Marta; Arroja, Bruno; Lago, Paula; Rosa, Isadora; Sousa, Helena TavaresBackgroundTimely stratification of Crohn's disease (CD) is essential for patients' management. The use of noninvasive accurate biomarkers is key to monitor treatment and to pursue mucosal healing, the ultimate treatment endpoint in CD. ObjectiveWe aimed to evaluate the performance of readily available biomarkers and develop risk matrices to predict CD progression. MethodsData from 289 CD patients receiving infl...
Towards a greener endoscopy: considerations on the strategies to improve sustai...
Neves, Joao; Roseira, Joana; Cunha, Miguel F.; Pellino, Gianluca; Sampietro, Gianluca M.; Rodríguez de Santiago, EnriqueClimate crisis is dramatically changing life on earth. Environmental sustainability and waste management are rapidly gaining centrality in quality improvement strategies of healthcare, especially in procedure- dominant fields such as gastroenterology and digestive endoscopy. Therefore, healthcare interventions and endoscopic procedures must be evaluated through the ‘triple bottom line’ of financial, social, and...