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Desmoplastic fibroblastoma (collagenous fibroma) on the mandibular ridge: case ...
Isaias,Pedro Henrique Chaves; Bezerra,Thâmara Manoela Marinho; Chaves,Filipe Nobre; Alves,Ana Paula Negreiros Nunes; Pereira,Karuza Maria AlvesAbstract The desmoplastic fibroblastoma (DF) is a rare benign soft-tissue tumor of fibroblastic and myofibroblastic origin, and its occurrence in the oral cavity is rare. This study details a new case of an elevated lesion in the alveolar ridge of a 59-year-old woman, painful during mastication. The histopathological exam showed non-encapsulated stellate-to-spindle cells proliferation in a hypocellular collagen...
Anthelmintic activity of nanoencapsulated carvacryl acetate against gastrointes...
André,Weibson Paz Pinheiro; Paiva Junior,José Ribamar de; Cavalcante,Géssica Soares; Ribeiro,Wesley Lyeverton Correia; Araújo Filho,José Vilemar deAbstract The objective of this study was to evaluate the efficacy of carvacryl acetate (CVA) and nanoencapsulated CVA (nCVA) on gastrointestinal nematodes of sheep. The CVA was nanoencapsulated with chitosan/gum arabic and the efficacy of nanoencapsulation (EE), yield, zeta potential, nanoparticle morphology and release kinetics at pH 3 and 8 were analyzed. Acute and subchronic toxicity were evaluated in rodent...
Multifocal oral melanoacanthoma associated with Addison’s disease and hyperthyr...
Dantas,Thinali Sousa; Nascimento,Isabelly Vidal do; Verde,Maria Elisa Quezado Lima; Alves,Ana Paula Negreiros Nunes; Sousa,Fabrício BituSUMMARY Oral melanoacanthoma is a mucocutaneous, pigmented, rare, benign, and probably reactive lesion. This paper reports for the first time in the literature a case of multifocal oral melanoacanthoma in a patient diagnosed with Addison’s disease and concomitant Graves’ disease with hyperthyroidism. The patient presented with oral pigmented lesions, which were hypothesized to be mucosal pigmentation associated...
Expression of S-100, EMA, CD34 and presence of mast cells in eight oral neurofi...
Oliveira,Francisco Artur Forte; Fernandes,Clarissa Pessoa; Mota,Mário Rogério Lima; Sousa,Fabrício Bitu; Silva,Malena Regina de Freitas eINTRODUCTION: The rarity of oral neurofibromas (ONs) generates problems regarding their epidemiological and immunohistochemical characterization. OBJECTIVES: The aim of this study was to evaluate the expression of different markers in ONs and review epidemiologic data reported in the literature. MATERIAL AND METHODS: Clinicopathologic, immunohistochemical (markers S-100, epithelial membrane antigen [EMA], CD34)...
Experimental model of traumatic ulcer in the cheek mucosa of rats
Cavalcante,Galyléia Meneses; Paula,Renata Janaína Sousa de; Souza,Leonardo Peres de; Sousa,Fabrício Bitu; Mota,Mário Rogério LimaPURPOSE: To establish an experimental model of traumatic ulcer in rat cheek mucosa for utilization in future alternative therapy studies. METHODS: A total of 60 adult male rats (250 - 300g) were used. Ulceration of the left cheek mucosa was provoked by abrasion using a nº 15 scalpel blade. The animals were observed for 10 days, during which they were weighed and their ulcers were measured. The histological char...
Radiographic and histological evaluation of bisphosphonate alendronate and meto...
Alves,Ana Paula Negreiros Nunes; Pessoa,Cláudia do Ó; Costa-Lotufo,Letícia; Moraes Filho,Manoel OdoricoPURPOSE: To investigate the effects of bisphosphosnate alendronate (ALD) and metotrexate (MTX) on an experimental model of Walker 256 carcinosarcoma developed in the oral cavity of rats. METHODS Walker 256 carcinosarcoma cell suspension (0,1 mL) containing 10(6) cell/mL was implanted in the alveoli of the first and second molars. The animals were divided and treated with saline, MTX, ALD, and MTX plus ALD. Late...
Modelo experimental de tumor na cavidade oral de ratos com carcinossarcoma de W...
Alves,Ana Paula Negreiros Nunes; Guedes,Rafael Cardoso; Costa-Lotufo,Letícia Veras; Moraes,Maria Elisabete Amaral de; Pessoa,Cláudia do ÓOBJETIVO: Estabelecer um modelo experimental de desenvolvimento tumoral na cavidade oral de ratos, permitindo, assim, o estudo da osteólise induzida pelo tumor nos ossos do complexo maxilomandibular como também nas estruturas dentais, através da caracterização histomorfológica da reabsorção óssea e dentária. MÉTODOS: Uma suspensão de células tumorais (0,1mL) do Carcinossarcoma de Walker 256, na concentração de ...