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Natural history of familial cerebral cavernous malformation syndrome in childre...

Geraldo, Ana Filipa; Alves, Cesar Augusto P. F.; Luis, Aysha; Tortora, Domenico; Guimarães, Joana; Abreu, Daisy; Reimão, Sofia; Pavanello, Marco

Purpose: There is limited data concerning neuroimaging findings and longitudinal evaluation of familial cerebral cavernous malformations (FCCM) in children. Our aim was to study the natural history of pediatric FCCM, with an emphasis on symptomatic hemorrhagic events and associated clinical and imaging risk factors. Methods: We retrospectively reviewed all children diagnosed with FCCM in four tertiary pediatric...


Spinal involvement in pediatric familial cavernous malformation syndrome

Geraldo, Ana Filipa; Luis, Aysha; Alves, Cesar Augusto P. F.; Tortora, Domenico; Guimarães, Joana; Reimão, Sofia; Pavanello, Marco; de Marco, Patrizia

Purpose: The aim of the study was to assess the prevalence and characteristics of spinal cord cavernous malformations (SCCM) and intraosseous spinal vascular malformations (ISVM) in a pediatric familial cerebral cavernous malformation (FCCM) cohort and evaluate clinico-radiological differences between children with (SCCM +) and without (SCCM-) SCCM. Methods: All patients with a pediatric diagnosis of FCCM evalu...


Use of porcelain laminate veneers in dentistry – main contraindications

Rossi, Andrea

Dental veneers are thin layers of ceramic that are applied to the outer surface of the tooth, coating them and changing their shape, color, length and position. Like any medical and dental procedure, the application of aesthetic veneers also includes contraindications that can generate some problems. The purpose of this review is to analyze the main contraindications of porcelain laminate veneers placement and ...


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