The expansion of 2,4-D consumption raises concerns about the environment and especially human health, as exposure to this chemical agent can cause harmful effects to the body. The aim of this research was to histopathologically evaluate the nasal epithelium and the hematological profile of rats submitted to chronic inhaled spraying of the 2,4-D herbicide. Forty adult male Wistar rats were used, divided into 4 g...
Familial Hypercholesterolemia is responsible for the increase in the levels of total cholesterol and LDL-cholesterol, which can cause a sharp increase in cardiovascular diseases. PCSK9 (convertase 1) is a highly expressed gene in liver, intestine and kidney. When synthesized and mutated, these small genetic variations end up helping in the regulation of LDL-Cholesterol, in addition, PCSK9 binding to LDL-Recepto...
Made available in DSpace on 2018-12-11T16:55:00Z (GMT). No. of bitstreams: 0 Previous issue date: 2018-01-01; The synthetic hormone sodium levothyroxine (LTX) is one of the most prescribed drugs in the world and the most effective in hypothyroidism treatment. The presence of LTX in the environment has become a matter of major concern due to the widespread use of this hormone and by the fact that it is only part...
The hypertensive disorders of pregnancy (SHG) have variable intensity according to their type. This study aimed to describe the demographic characteristics and maternal-fetal morphometric changes of placenta in different types of SHG by retrospective analysis of medical records of hypertensive patients with placentas evaluated morphologically, processed for immunohistochemistry using monoclonal antibody anti-hu...