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Deep brain stimulation of the anterior nucleus of the thalamus in drug-resistan...

Peltola, Jukka; Colon, Albert J.; Pimentel, José; Coenen, Volker A.; Gil-Nagel, Antonio; Gonçalves Ferreira, António; Lehtimäki, Kai; Ryvlin, Philippe

Background and objectives: The efficacy of deep brain stimulation of the anterior nucleus of the thalamus (ANT DBS) in patients with drug-resistant epilepsy (DRE) was demonstrated in the double-blind Stimulation of the Anterior Nucleus of the Thalamus for Epilepsy randomized controlled trial. The Medtronic Registry for Epilepsy (MORE) aims to understand the safety and longer-term effectiveness of ANT DBS therap...


Autoimmune encephalitis With mGluR1 antibodies presenting with Epilepsy, but wi...

Vinke, Anita M.; Zong, Shenghua; Janssen, Josien H.; Hoffmann, Carolin Correia; Mané-Damas, Marina; Damoiseaux, Jan G.M.C.; de Vries, J.M.

Objective To describe the unique case history of a patient with mGluR1 antibodies, with mainly limbic and without cerebellar symptoms. Methods A 50-year-old woman initially presented with focal seizures with epigastric rising and deja-vu sensations, next to cognitive complaints, and musical auditory hallucinations. MRI, EEG, and neuronal autoantibody tests were performed. Results EEG findings showed slow and sh...


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