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Biomarkers in pulmonary infections

Povoa, Pedro; Coelho, Luís; Cidade, José Pedro; Ceccato, Adrian; Morris, Andrew Conway; Salluh, Jorge; Nobre, Vandack; Nseir, Saad

Publisher Copyright: © The Author(s) 2024.; Severe acute respiratory infections, such as community-acquired pneumonia, hospital-acquired pneumonia, and ventilator-associated pneumonia, constitute frequent and lethal pulmonary infections in the intensive care unit (ICU). Despite optimal management with early appropriate empiric antimicrobial therapy and adequate supportive care, mortality remains high, in part a...


Relationship between corticosteroid use and incidence of ventilator-associated ...

Saura, Ouriel; Rouzé, Anahita; Martin-Loeches, Ignacio; Povoa, Pedro; Kreitmann, Louis; Torres, Antoni; Metzelard, Matthieu; Du Cheyron, Damien

Funding This study was supported in part by a grant from the French government through the « Programme Investissement d’Avenir» (I-SITE ULNE) managed by the Agence Nationale de la Recherche (coVAPid project). Prof. Ignacio Martin-Loeches has been supported by SFI (Science Foundation Ireland), Grant number 20/COV/0038. The funders of the study had no role in the study design, data collection, analysis or interpr...


Relationship between ventilator-associated pneumonia and mortality in COVID-19 ...

Nseir, Saad; Martin-Loeches, Ignacio; Povoa, Pedro; Metzelard, Matthieu; Du Cheyron, Damien; Lambiotte, Fabien; Tamion, Fabienne; Labruyere, Marie

Funding: This study was supported in part by a grant from the French government through the «Programme Investissement d’Avenir» (I-SITE ULNE) managed by the Agence Nationale de la Recherche (coVAPid project). The funders of the study had no role in the study design, data collection, analysis, or interpreta tion, writing of the report, or decision to submit for publication.; BACKGROUND: Patients with SARS-CoV-2 ...


Correction to

Nseir, Saad; Martin-Loeches, Ignacio; Povoa, Pedro; Metzelard, Matthieu; Du Cheyron, Damien; Lambiotte, Fabien; Tamion, Fabienne; Labruyere, Marie

Following publication of the original article [1], the authors identified an error in the Abstract and Results section. The correct numbers and text are given hereafter. Abstract VAP was associated with significantly higher risk for 28-day mortality in SARS-CoV-2 group (adjusted HR 1.65 (95% CI 1.11–2.46), p = 0.013), but not in influenza (1.74 (0.99–3.06), p = 0.052), or no viral infection groups (1.13 (0.68–1...


Impact of chronic obstructive pulmonary disease on incidence, microbiology and ...

Rouzé, Anahita; Boddaert, Pauline; Martin-loeches, Ignacio; Povoa, Pedro; Rodriguez, Alejandro; Ramdane, Nassima; Salluh, Jorge; Houard, Marion

Objectives: To determine the impact of chronic obstructive pulmonary disease (COPD) on incidence, microbiology, and outcomes of ventilator-associated lower respiratory tract infections (VA-LRTI). Methods: Planned ancillary analysis of TAVeM study, including 2960 consecutive adult patients who received invasive mechanical ventilation (MV) > 48 h. COPD patients (n = 494) were compared to non-COPD patients (n = 24...


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