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Insights from Portuguese Nephrologists and Rheumatologists Concerning the Treat...

Ferreira, Inês; Águeda, Ana; Belino, Carolina; Schau, Bruno; Rovisco, João; Ferreira, Carina

Introduction: Antineutrophilic cytoplasmic antibodies-associated vasculitis (AAV) encompasses granulomatosis with polyangiitis, microscopic polyangiitis, and eosinophilic granulomatosis with polyangiitis. These rare diseases are characterized by an exaggerated immune response in blood vessels, leading to inflammation, vascular injury, ischemia, and necrosis of affected tissues and organs. Despite the existence ...

Date: 2024   |   Origin: Acta Médica Portuguesa

Ultrasonography Reliability in the Detection of Inflammatory and Structural Abn...

Brites, Luisa; Santiago, Mariana; Rovisco, João; Freitas, João; Silva, José A. P.; Silva, Inês; Teixeira, Filipa; Faria, Daniela S.; Silva, Cândida G.

Background Ultrasonography is an image technique that allows rheumatologists to visualize structural and inflammatory changes within a joint. The objective of this study was to assess the interobserver and intraobserver reliability of musculoskeletal ultrasound (US) in the detection of inflammatory and destructive joint changes in patients with polyarthritis. Methods A Delphi exercise was undertaken to standard...

Date: 2021   |   Origin: IC-online

Eligibility criteria for biologic disease-modifying antirheumatic drugs in axia...

Marona, Jose; Sepriano, Alexandre; Rodrigues-Manica, Santiago; Pimentel-Santos, Fernando; Mourão, Ana Filipa; Gouveia, Nélia; Branco, Jaime Cunha

Objectives To compare definitions of high disease activity of the Ankylosing Spondylitis Disease Activity Score (ASDAS) and Bath Ankylosing Spondylitis Disease Activity Index (BASDAI) in selecting patients for treatment with biologic disease-modifying antirheumatic drugs (bDMARDs). Methods Patients from Rheumatic Diseases Portuguese Register ( R euma. pt) with a clinical diagnosis of axial spondyloarthritis (ax...


Eligibility criteria for biologic disease-modifying antirheumatic drugs in axia...

Marona, Jose; Sepriano, Alexandre; Rodrigues-Manica, Santiago; Pimentel-Santos, Fernando; Mourão, Ana Filipa; Gouveia, Nélia; Branco, Jaime Cunha

Objectives: To compare definitions of high disease activity of the Ankylosing Spondylitis Disease Activity Score (ASDAS) and Bath Ankylosing Spondylitis Disease Activity Index (BASDAI) in selecting patients for treatment with biologic disease-modifying antirheumatic drugs (bDMARDs). Methods: Patients from Rheumatic Diseases Portuguese Register (Reuma.pt) with a clinical diagnosis of axial spondyloarthritis (axS...


Effectiveness of switching between TNF inhibitors in patients with axial spondy...

Manica, Santiago Rodrigues; Sepriano, Alexandre; Pimentel-Santos, Fernando; Gouveia, Nélia; Barcelos, Anabela; Branco, Jaime C.; Bernardes, Miguel

Background: To investigate whether the reason to discontinue the first TNF inhibitor (TNFi) affects the response to the second TNFi in axial spondyloarthritis (axSpA). Methods: Patients with axSpA from the Rheumatic Diseases Portuguese Register (ReumaPt), who discontinued their first TNFi and started the second TNFi between June 2008 and May 2018, were included. Response was assessed by the Ankylosing Spondylit...


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