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Transcontinental dissemination of the L2b/D-Da recombinant Chlamydia trachomati...

Borges, Vítor; Isidro, Joana; Correia, Cristina; Cordeiro, Dora; Vieira, Luís; Lodhia, Zohra; Fernandes, Cândida; Rodrigues, Ana Maria; Azevedo, Jacinta

Previously, we identified a Chlamydia trachomatis Lymphogranuloma venereum (LGV) recombinant strain possessing a unique non-LGV ompA genotype. Here, culture-independent genome sequencing confirms its circulation in Europe, Middle East and North America, and unveils genetic evidence of emergence of antibiotic resistance. Multi-country and systematic molecular surveillance is needed.


Transcontinental Dissemination of the L2b/D-Da Recombinant Chlamydia trachomati...

Borges, Vítor; Isidro, Joana; Correia, Cristina; Cordeiro, Dora; Vieira, Luís; Lodhia, Zohra; Fernandes, Cândida; Rodrigues, Ana Maria; Azevedo, Jacinta

Previously, we identified a Chlamydia trachomatis lymphogranuloma venereum (LGV) recombinant strain possessing a non-LGV ompA genotype. Here, culture-independent genome sequencing confirms its circulation in Europe, Middle East, and North America, and unveils emergence of antibiotic resistance. Broad surveillance is needed.


Chlamydia trachomatis: when the virulence-associated genome backbone imports a ...

Borges, Vítor; Cordeiro, Dora; Salas, Ana Isabel; Lodhia, Zohra; Correia, Cristina; Isidro, Joana; Fernandes, Cândida; Rodrigues, Ana Maria

Chlamydia trachomatis is the most prevalent sexually transmitted bacterium worldwide and the causative agent of trachoma. Its strains are classified according to their ompA genotypes, which are strongly linked to differential tissue tropism and disease outcomes [ocular disease, urogenital disease and lymphogranuloma venereum (LGV)]. While the genome-based species phylogenetic tree presents four main clades corr...


Chlamydia trachomatis: when the virulence-associated genome backbone imports a ...

Borges, Vítor; Cordeiro, Dora; Salas, Ana Isabel; Lodhia, Zohra; Correia, Cristina; Isidro, Joana; Fernandes, Cândida; Rodrigues, Ana Maria

Chlamydia trachomatis is the most prevalent sexually transmitted bacterium worldwide and the causative agent of trachoma. Its strains are classified according to their ompA genotypes, which are strongly linked to differential tissue tropism and disease outcomes [ocular disease, urogenital disease and lymphogranuloma venereum (LGV)]. While the genome-based species phylogenetic tree presents four main clades corr...


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