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Temporal change in minimum mortality temperature under changing climate: A mult...

Yang, Daewon; Hashizume, Masahiro; Tobías, Aurelio; Honda, Yasushi; Roye, Dominic; Oh, Jaemin; Dang, Tran Ngoc; Kim, Yoonhee; Abrutzky, Rosana

Background: The minimum mortality temperature (MMT) or MMT percentile (MMTP) is an indicator of population susceptibility to nonoptimum temperatures. MMT and MMTP change over time; however, the changing directions show region-wide heterogeneity. We examined the heterogeneity of temporal changes in MMT and MMTP across multiple communities and in multiple countries. Methods: Daily time-series data for mortality a...


Temperature frequency and mortality: Assessing adaptation to local temperature

Wu, Yao; Wen, Bo; Gasparrini, Antonio; Armstrong, Ben; Sera, Francesco; Lavigne, Eric; Li, Shanshan; Guo, Yuming; Overcenco, Ala; Urban, Aleš

Assessing the association between temperature frequency and mortality can provide insights into human adaptation to local ambient temperatures. We collected daily time-series data on mortality and temperature from 757 locations in 47 countries/regions during 1979–2020. We used a two-stage time series design to assess the association between temperature frequency and all-cause mortality. The results were pooled ...


Impact of population aging on future temperature-related mortality at different...

Chen, Kai; de Schrijver, Evan; Sivaraj, Sidharth; Sera, Francesco; Scovronick, Noah; Jiang, Leiwen; Roye, Dominic; Lavigne, Eric; Kyselý, Jan

Older adults are generally amongst the most vulnerable to heat and cold. While temperature-related health impacts are projected to increase with global warming, the influence of population aging on these trends remains unclear. Here we show that at 1.5 °C, 2 °C, and 3 °C of global warming, heat-related mortality in 800 locations across 50 countries/areas will increase by 0.5%, 1.0%, and 2.5%, respectively; amon...


Seasonality of mortality under climate change: a multicountry projection study

Madaniyazi, Lina; Armstrong, Ben; Tobias, Aurelio; Mistry, Malcolm N.; Bell, Michelle L.; Urban, Aleš; Kyselý, Jan; Ryti, Niilo; Cvijanovic, Ivana

Background: Climate change can directly impact temperature-related excess deaths and might subsequently change the seasonal variation in mortality. In this study, we aimed to provide a systematic and comprehensive assessment of potential future changes in the seasonal variation, or seasonality, of mortality across different climate zones. Methods: In this modelling study, we collected daily time series of mean ...


Impact of population aging on future temperature-related mortality at different...

Chen, Kai; de Schrijver, Evan; Sivaraj, Sidharth; Sera, Francesco; Scovronick, Noah; Jiang, Leiwen; Roye, Dominic; Lavigne, Eric; Kyselý, Jan

Older adults are generally amongst the most vulnerable to heat and cold. While temperature-related health impacts are projected to increase with global warming, the influence of population aging on these trends remains unclear. Here we show that at 1.5 °C, 2 °C, and 3 °C of global warming, heat-related mortality in 800 locations across 50 countries/areas will increase by 0.5%, 1.0%, and 2.5%, respectively; amon...


Global, regional, and national burden of mortality associated with cold spells ...

Gao, Yuan; Huang, Wenzhong; Zhao, Qi; Ryti, Niilo; Armstrong, Ben; Gasparrini, Antonio; Tong, Shilu; Pascal, Mathilde; Urban, Aleš; Zeka, Ariana

Background: Exposure to cold spells is associated with mortality. However, little is known about the global mortality burden of cold spells. Methods: A three-stage meta-analytical method was used to estimate the global mortality burden associated with cold spells by means of a time series dataset of 1960 locations across 59 countries (or regions). First, we fitted the location-specific, cold spell-related morta...


Joint effect of heat and air pollution on mortality in 620 cities of 36 countries

Stafoggia, Massimo; Michelozzi, Paola; Schneider, Alexandra; Armstrong, Ben; Scortichini, Matteo; Rai, Masna; Achilleos, Souzana; Alahmad, Barrak

Background: The epidemiological evidence on the interaction between heat and ambient air pollution on mortality is still inconsistent. Objectives: To investigate the interaction between heat and ambient air pollution on daily mortality in a large dataset of 620 cities from 36 countries. Methods: We used daily data on all-cause mortality, air temperature, particulate matter ≤ 10 μm (PM10), PM ≤ 2.5 μm (PM2.5), n...


Interactive effects of ambient fine particulate matter and ozone on daily morta...

Liu, Cong; Chen, Renjie; Sera, Francesco; Vicedo-Cabrera, Ana Maria; Guo, Yuming; Tong, Shilu; Lavigne, Eric; Correa, Patricia Matus

Objective: To investigate potential interactive effects of fine particulate matter (PM2.5) and ozone (O3) on daily mortality at global level. Design: Two stage time series analysis. Setting: 372 cities across 19 countries and regions. Population: Daily counts of deaths from all causes, cardiovascular disease, and respiratory disease. Main outcome measure: Daily mortality data during 1994-2020. Stratified analys...


Short-Term Association between Sulfur Dioxide and Mortality: A Multicountry Ana...

O’Brien, Edward; Masselot, Pierre; Sera, Francesco; Roye, Dominic; Breitner, Susanne; Ng, Chris Fook Sheng

Background: Epidemiological evidence on the health risks of sulfur dioxide (sulfur dioxide SO2) is more limited compared with other pollutants, and doubts remain on several aspects, such as the form of the exposure–response relationship, the potential role of copollutants, as well as the actual risk at low concentrations and possible temporal variation in risks. Objectives: Our aim was to assess the short-term ...


Effect modification of greenness on the association between heat and mortality:...

Choi, Hayon Michelle; Lee, Whanhee; Roye, Dominic; Heo, Seulkee; Urban, Aleš; Entezari, Alireza; Vicedo-Cabrera, Ana Maria; Zanobetti, Antonella

Background: Identifying how greenspace impacts the temperature-mortality relationship in urban environments is crucial, especially given climate change and rapid urbanization. However, the effect modification of greenspace on heat-related mortality has been typically focused on a localized area or single country. This study examined the heat-mortality relationship among different greenspace levels in a global s...


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