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Efeitos da morte cerebral na microvasculatura pulmonar em um modelo experimenta...

Simas,Rafael; Zanoni,Fernando Luiz; Silva,Raphael dos Santos Coutinho e; Moreira,Luiz Felipe Pinho

RESUMO Objetivo A morte cerebral (MC) desencadeia alterações hemodinâmicas e inflamatórias importantes, comprometendo a viabilidade dos órgãos empregados em transplantes. Para compreender melhor as alterações microcirculatórias nos pulmões de doadores com MC, o presente estudo investigou a microcirculação pulmonar em um modelo de roedor com MC via microscopia intravital. Métodos Ratos Wistar machos foram aneste...

Date: 2020   |   Origin: Oasisbr

Controlling false positive rates in research and its clinical implications

Simas,Rafael; Maestri,Felipe; Normando,David

Date: 2014   |   Origin: Oasisbr

Influence of brain death and associated trauma on solid organ histological char...

Simas,Rafael; Kogiso,Diogo Haruo; Correia,Cristiano de Jesus; Silva,Luiz Fernando Ferraz da; Silva,Isaac Azevedo; Cruz,José Walber Miranda Costa

PURPOSE: To evaluate histopathological alterations triggered by brain death and associated trauma on different solid organs in rats. METHODS: Male Wistar rats (n=37) were anesthetized with isoflurane, intubated and mechanically ventilated. A trepanation was performed and a balloon catheter inserted into intracraninal cavity and rapidly inflated with saline to induce brain death. After induction, rats were monit...

Date: 2012   |   Origin: Oasisbr

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