4 documents found, page 1 of 1
Radiochemical and biological evaluation of novel Sm-153/Ho-166-amino acid-chito...
Marques, F; Gano, L; Batista, MKS; Gomes, CAR; Gomes, P; Santos, ISm-153/Ho-166-chitosan complexes have been considered promising agents for internal radiation therapy. By direct administration, complexes solution converts into a gel, at physiological pH, allowing its retention for a long time. Herein, we report on the synthesis of Sm-153/Ho-166 complexes with the novel amino acid-chitosan polymers, N-(gamma-propanoylvalin)-chitosan (CHICO-val) and N-(gamma-propanoyl-aspartic...
13- and 14-membered macrocyclic ligands containing methylcarboxylate or methylp...
Marques, F; Gano, L; Campello, MP; Lacerda, S; Santos, I; Lima, LMP; Costa, J; Antunes, P; Delgado, R
Sm-153 and Ho-166 complexes with tetraaza macrocycles containing pyridine and m...
Marques, F; Guerra, KP; Gano, L; Costa, J; Campello, MP; Lima, LMP; Delgado, R; Santos, IA set of tetraaza macrocycles containing pyridine and methylcarboxylate (ac(3)py14) or methylphosphonate (MeP(2)py14 and P(3)py14) pendant arms were prepared and their stability constants with La3+, Sm3+, Gd3+ and Ho3+ determined by potentiometry at 25degreesC and 0.10 M ionic strength in NMe4NO3. The metal:ligand ratio for Sm-153 and Ho-166 and for ac(3)py14, MeP(2)py14 and P(3)py14, as well as the pH of the r...
Lanthanide complexes with 13 and 14-membered tetraazamacrocycles
Campelo, MP; Costa, J; Delgado, R; Gano, L; Marques, F; Santos, I