3 documents found, page 1 of 1
Brazilian guidelines for the pharmacological treatment of idiopathic pulmonary ...
Baddini-Martinez,José; Ferreira,Juliana; Tanni,Suzana; Alves,Luis Renato; Cabral Junior,Benedito Francisco; Carvalho,Carlos Roberto RibeiroABSTRACT Idiopathic pulmonary fibrosis (IPF) is a form of chronic interstitial lung disease of unknown cause, which predominantly affects elderly men who are current or former smokers. Even though it is an uncommon disease, it is of great importance because of its severity and poor prognosis. In recent decades, several pharmacological treatment modalities have been investigated for the treatment of this disease...
Translation and cultural adaptation of the Sleep Apnea Clinical Score for use i...
Lapas,Verônica Sobral Camara; Faria,Anamelia Costa; Rufino,Rogério Lopes; Costa,Cláudia Henrique daABSTRACT Objective: To translate the Sleep Apnea Clinical Score (SACS) into Brazilian Portuguese and adapt it to the cultural setting, validating it for use as a screening method for polysomnography and as a tool to quantify the risk of obstructive sleep apnea syndrome in individuals in Brazil. Methods: The translation was performed by two professionals, with subsequent synthesis of the translations. From that ...
Rituximab for the therapy of systemic sclerosis: a series of 10 cases in a sing...
Vilela,Verônica Silva; Maretti,Giselle Baptista; Gama,Lívia Marques da Silva; Costa,Claudia Henrique da; Rufino,Rogério Lopes; Levy,Roger A.Abstract Systemic sclerosis (SSc) is a chronic autoimmune disease with a high morbidity and mortality. Although cyclophosphamide is effective for severe and refractory cases, there is demand for new treatments. The biological treatment with B-cell depletion with rituximab (RTX) has demonstrated efficacy for this demand in open-label studies. Objective This study was conducted with the aim to retrospectively eva...