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Issue 2 - “Update on adverse respiratory effects of indoor air pollution” Part ...

Rufo, JC; Annesi-Maesano, I; Carreiro-Martins, P; Moreira, A; Sousa, AC; Pastorinho, MR; Neuparth, N; Taborda-Barata, L

Objective To quantify the impact of different air pollutants on respiratory health based on robust estimates based on international data and to summarise the evidence of associations between indoor exposure to those pollutants and respiratory morbidity in the Portuguese population. Results Several systematic reviews and meta-analyses (MA) at the world level demonstrate the impact of indoor air quality on respir...


Mediterranean Diet and Airway Inflammation in School-Aged Children

Rodrigues, M; de Castro Mendes, F; Padrão, Patrícia; Delgado, L; Paciência, I; Barros, Renata; Rufo, JC; Silva, D; Moreira, André; Moreira, Pedro

<jats:p>There seems to exist an intricate relationship between airway inflammation, body mass index (BMI), and diet. The intake of specific foods or food groups has been suggested to suppress the oxidative stress and inflammatory processes that characterize airway inflammation, but little is known about dietary patterns and their complex interplay with BMI and airway inflammation. Therefore, this cross-sectiona...


Diet Quality and Exhaled Breath Condensate Markers in a Sample of School-Aged C...

Rodrigues, M; Mendes, FD; Paciencia, I; Rufo, JC; Silva, D; Delgado, L; Moreira, André; Moreira, Pedro

Exhaled breath condensate (EBC) analysis is a recently developed, non-invasive method used to identify and quantify biomarkers, mainly those coming from the lower respiratory tract. It seems that diet can influence the airway's inflammation and change the exhaled breath composition. This study aimed to assess the association between diet quality intake and markers in EBC among school-aged children. A cross-sect...


Does the Mediterranean Dietary Pattern Promote Lower Sodium Urinary Excretion i...

Rodrigues, M; Mendes, FD; Padrão, Patrícia; Delgado, L; Barros, Renata; Rufo, JC; Silva, D; Moreira, André; Moreira, Pedro

An adequate sodium intake is related to various health benefits. Parallelly, the Mediterranean diet (MD) is a dietary pattern known for its many positive impacts on health. Nonetheless, the association between adherence to the MD and sodium urinary excretion is scarce, even more in children. This study aimed to assess the association between MD adherence and the excretion of sodium, as a proxy of intake. This c...


Dietary Acid Load Modulation of Asthma-Related miRNAs in the Exhaled Breath Con...

Mendes, FC; Paciencia, I; Rufo, JC; Silva, D; Delgado, L; Moreira, André; Moreira, Pedro

Individual nutrients and bioactive compounds have been implicated in the expression of microRNAs (miRNAs), which are related to inflammation and asthma. However, evidence about the impact of diet is scarce. Therefore, we aimed to assess the association between dietary acid load and asthma-related miRNA in the exhaled breath condensate (EBC) of school-aged children. This cross-sectional analysis included 150 par...


Green and blue spaces and lung function in the Generation XXI cohort: a life-co...

Almeida, DQ; Paciência, I; Moreira, C; Rufo, JC; Moreira, A; Santos, AC; Barros, H; Ribeiro, AI

Background Exposure to natural environments may affect respiratory health. This study examined the association of exposure to green and blue spaces with lung function in children, and assessed the mediation effect of air pollution and physical activity. Methods The study used data from the Generation XXI, a population-based birth cohort from the Porto Metropolitan Area (Portugal). Residential Normalised Differe...


Increasing Vegetable Diversity Consumption Impacts the Sympathetic Nervous Syst...

Mendes, FD; Paciencia, I; Rufo, JC; Farraia, M; Silva, D; Padrão, Patrícia; Delgado, L; Garcia Larsen, V; Moreira, André; Moreira, Pedro

Evidence about the impact of vegetable and fruit diversity consumption on the autonomic nervous system (ANS) functioning is scarce. In this cross-sectional study (513 participants, 49.9% girls aged 7 to 12 years), we evaluated the association between vegetable and fruit diversity consumption and the ANS in school-aged children. Dietary intake was collected using a single 24-h recall questionnaire. Fruit and veg...


Exhaled breath condensate pH determinants in school-aged children: A population...

Tiago Rama; Paciencia, I; Rufo, JC; Silva, D; Cunha, P; Severo, M; Padrão, Patrícia; Moreira, Pedro; Delgado, L; Moreira, André

Background Exhaled breath condensate (EBC) pH is a promising biomarker of airway inflammation. Lack of method standardization and interstudy variability precludes its use in clinical practice. While endogenous determinants have been described, underlying mechanisms for variability are mostly unknown. Thus, we aimed to assess the association between asthma and EBC pH in children, while studying potential environ...


Higher diversity of vegetable consumption is associated with less airway inflam...

Mendes, FD; Paciencia, I; Rufo, JC; Farraia, M; Silva, D; Padrão, Patrícia; Delgado, L; Garcia Larsen, V; Moreira, A; Moreira, Pedro

Background A diet rich in fruits and vegetables has been suggested to counteract the oxidative stress and inflammation that characterize asthma. We aimed to assess the association between vegetable and fruit diversity consumption and asthma and its related outcomes in school-aged children. Methods Participants included 647 children (49% females, aged 7-12 years) recruited from 20 public schools across the city ...


The Influence of Eating at Home on Dietary Diversity and Airway Inflammation in...

de Castro Mendes, F; Cunha, P; Paciencia, I; Rufo, JC; Farraia, M; Silva, D; Padrão, Patrícia; Delgado, L; Moreira, André; Moreira, Pedro

Considering the negative impact of a lack of dietary diversity on children's nutritional status, we aimed to describe dietary variety according to eating at home frequency and assessed its association with respiratory outcomes in school-aged children. This cross-sectional study included 590 children (49% girls) aged 7 to 12 years from 20 public schools located in city of Porto, Portugal. Daily frequency of eati...


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