86 documents found, page 1 of 9

Cholesterol Functionalized Nanoparticles Are Effective against Helicobacter pyl...

Helicobacter pylori chronic infection is the highest risk factor for the development of gastric cancer, being this Gram-negative bacterium classified as carcinogenic. The mounting resistance of H. pylori to antibiotics calls for innovative therapeutic strategies. Here, the proof-of-concept studies that support the development of a "trojan horse" therapeutic strategy based on cholesterol-grafted nanoparticles (C...

Haute cuisine: A mixed-methods approach to assess gastronomic offer nutritional...

In recent years, a growing interest of society for out-of-home food experiences has been observed, concurrently with an increasing number of restaurants associated to haute cuisine. However, data on the nutritional adequacy of the meals offered in these restaurants is lacking. This study aimed to evaluate the perception of haute cuisine chefs in Portugal about the importance attributed to food and nutrition rec...

Ter filhos afeta de forma diferente a vida pessoal e profissional de pais e mães?

A parentalidade, outrora aceite como uma obrigação natural, é hoje uma escolha mais autónoma. Contudo, as pressões sociais que recaem sobre mulheres e homens no momento de serem pais tornam a vivência desta experiência ainda mais desafiante. Por permanecerem enraizadas conceções tradicionais sobre a divisão do trabalho, que atribuem ao homem o papel de provedor da família e à mulher o papel de cuidadora, a pare...

The Impact of Sleep on Haematological Parameters in Firefighters

Sleep is a vital process that impacts biological functions such as cell renewal, bone regeneration, and immune system support. Disrupted sleep can interrupt erythropoiesis, leading to fewer red blood cells, reduced haemoglobin concentration, and decreased haematocrit levels, potentially contributing to haematological disorders. This is particularly concerning for shift workers for example firefighters. While pr...

Global age-sex-specific mortality, life expectancy, and population estimates in...

Background: Estimates of demographic metrics are crucial to assess levels and trends of population health outcomes. The profound impact of the COVID-19 pandemic on populations worldwide has underscored the need for timely estimates to understand this unprecedented event within the context of long-term population health trends. The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2021 provides n...

Multidisciplinary Development and Initial Validation of a Clinical Knowledge Ba...

Most mobile health (mHealth) decision support systems currently available for chronic obstructive respiratory diseases (CORDs) are not supported by clinical evidence or lack clinical validation. The development of the knowledge base that will feed the clinical decision support system is a crucial step that involves the collection and systematization of clinical knowledge from relevant scientific sources and its...

Epidemiology of Psoriasis in Portugal: A Population-Based Study

Introduction: Psoriasis is a common, chronic, and inflammatory skin disorder with a high personal, social and economic burden and important implica-tions for healthcare systems. The aim of this study was to provide an epidemiological characterization of individuals with psoriasis in Portugal.Material and Methods: A large observational, cross-sectional, nationwide, population-based survey study developed by the ...

Organic geochemistry and mineralogy suggest anthropogenic impact in speleothem ...

The network of lava tubes is one of the most unexploited natural wonders of the Galapagos Islands. Here, we provide the first morphological, mineralogical, and biogeochemical assessment of speleothems fromvolcanic caves of the Galapagos to understand their structure, composition, and origin, as well as to identify organic molecules preserved in speleothems. Mineralogical analyses revealed that moonmilk and cora...

From Illness to Resilience: Mediating Factors of Quality of Life in Patients wi...

A Comprehensive Look at In Vitro Angiogenesis Image Analysis Software

One of the complex challenges faced presently by tissue engineering (TE) is the development of vascularized constructs that accurately mimic the extracellular matrix (ECM) of native tissue in which they are inserted to promote vessel growth and, consequently, wound healing and tissue regeneration. TE technique is characterized by several stages, starting from the choice of cell culture and the more appropriate ...