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Recommendations by the Scientific Department of Neuroimmunology of the Brazilia...

Becker,Jefferson; Ferreira,Lis Campos; Damasceno,Alfredo; Bichuetti,Denis Bernardi; Christo,Paulo Pereira; Callegaro,Dagoberto

ABSTRACT The Scientific Department of Neuroimmunology of the Brazilian Academy of Neurology (DCNI/ABN) and Brazilian Committee for Treatment and Research in Multiple Sclerosis and Neuroimmunological Diseases (BCTRIMS) provide recommendations in this document for vaccination of the population with demyelinating diseases of the central nervous system (CNS) against infections in general and against the severe acut...

Date: 2021   |   Origin: Oasisbr

Migraine in 746 patients with multiple sclerosis

Fragoso,Yara Dadalti; Adoni,Tarso; Alves-Leon,Soniza V.; Apostolos-Pereira,Samira L.; Carneiro,Marcos A. Diniz; Chikota,Edila M.

ABSTRACT Migraine adds to the burden of patients suffering from multiple sclerosis (MS). The ID-migraine is a useful tool for screening migraine, and the Migraine Disability Assessment questionnaire can evaluate disease burden. The aim of the present study was to assess the presence and burden of migraine in patients with MS. Methods: Patients diagnosed with MS attending specialized MS units were invited to ans...

Date: 2019   |   Origin: Oasisbr

High levels of alexithymia in patients with multiple sclerosis

Eboni,Audred Cristina Biondo; Cardoso,Mariana; Dias,Felipe Moreira; Gama,Paulo Diniz da; Gomes,Sidney; Goncalves,Marcus Vinicius Magno

Abstract Alexithymia is a personality trait characterized by difficulties identifying and describing feelings. Some researchers describe high levels of alexithymia among patients with multiple sclerosis (MS) but literature data on this subject are scarce. Objective: The objective of the present study was to characterize findings of alexithymia in patients with MS. Methods: This cross-sectional case-control stud...

Date: 2018   |   Origin: Oasisbr

No correlation was observed between vitamin D levels and disability of patients...

Fragoso,Yara Dadalti; Adoni,Tarso; Alves-Leon,Soniza Vieira; Apostolos-Pereira,Samira L.; Arruda,Walter Oleschko; Brooks,Joseph B. Bidin

ABSTRACT Objective: Vitamin D has taken center stage in research and treatment of multiple sclerosis (MS). The objective of the present study was to assess the serum vitamin D levels of a large population of patients with MS and controls living in a restricted tropical area. Methods: Data from 535 patients with MS and 350 control subjects were obtained from 14 cities around the Tropic of Capricorn. Results: The...

Date: 2017   |   Origin: Oasisbr

Natalizumab adverse events are rare in patients with multiple sclerosis

Fragoso,Yára Dadalti; Alves-Leon,Soniza Vieira; Arruda,Walter Oleschko; Carvalho,Margarete de Jesus; Comini-Frota,Elizabeth Regina; Corrêa,Éber Castro

Objective To assess the prevalence and the profile of adverse events (AE) of natalizumab in patients with multiple sclerosis (MS). Methods Data collection from neurologists attending to patients with MS at specialized units in Brazil. Results Data from 103 patients attending the infusion centers of 16 MS units in 9 Brazilian states were included in the study. The total number of infusions was 1,042. Seventy-nin...

Date: 2013   |   Origin: Oasisbr

Nearly one-half of Brazilian patients with multiple sclerosis using natalizumab...

Fragoso,Yara Dadalti; Mendes,Maria Fernanda; Arruda,Walter Oleschko; Becker,Jefferson; Brooks,Joseph Bruno Bidin; Carvalho,Margarete de Jesus

Objective Natalizumab is a new and efficient treatment for multiple sclerosis (MS). The risk of developing progressive multifocal leukoencephalopathy (PML) during the use of this drug has created the need for better comprehension of JC virus (JCV) infection. The objective of the present study was to assess the prevalence of JCV-DNA in Brazilian patients using natalizumab. Method Qualitative detection of the JCV...

Date: 2013   |   Origin: Oasisbr

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