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Precise multiphase hydrogel engineering of miniaturized 3D cancer architectures...

Rial, Ramón; Guimarães, Carlos Ferreira; Gasperini, Luca; Brito, Alexandra; Costa, Rui R.; Ruso, Juan M.; Reis, R. L.

Understanding cancer biology and therapy responses requires accurate in vitro models that reflect tumor complexity. This work presents a multiphase microfluidic biofabrication approach for creating self-standing three-dimensional (3D) tumor models within hydrogel microfiber boundaries. A single framework enabled the fast generation of different in vitro cellular configurations, including discrete spheroids ...

Date: 2025   |   Origin: RepositóriUM - Universidade do Minho
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