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Mitochondrial variability as a source of extrinsic cellular noise

Johnston, Iain G; Gaal, Bernadett; Neves, Ricardo Pires das; Enver, Tariq; Iborra, Francisco J; Jones, Nick S

We present a study investigating the role of mitochondrial variability in generating noise in eukaryotic cells. Noise in cellular physiology plays an important role in many fundamental cellular processes, including transcription, translation, stem cell differentiation and response to medication, but the specific random influences that affect these processes have yet to be clearly elucidated. Here we present a m...

Date: 2012   |   Origin: Estudo Geral - Universidade de Coimbra
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