21 documents found, page 1 of 3

Ethnobotanical Inventory of Plants Used by Mountainous Rural Communities in NW ...

Mountains matter. Rural subsistence communities living in areas with high biodiversity, such as mountains, are hotspots of ecological knowledge. However, modern lifestyles may threaten this unique cultural heritage. Our study aimed to document and analyze information on plants used to fulfill the everyday needs of the people in three rural communities in NW Portugal. Fieldwork was carried out for a period of on...

Behavior Guidance during the Covid-19 Pandemic: Health Literacy as a Weapon aga...

Portugal was hit by COVID-19 on the 2nd of March 2020. For almost two months, the country was confined due to the declaration of the emergency state. The confinement was always conveyed by the media, who clearly guided citizens toward preventive behaviors and so became a means of fighting this pandemic by helping the country stay home. Several authors recognize the importance of health communication and health ...

Telomere maintenance mechanisms in cancer

Tumour cells can adopt telomere maintenance mechanisms (TMMs) to avoid telomere shortening, an inevitable process due to successive cell divisions. In most tumour cells, telomere length (TL) is maintained by reactivation of telomerase, while a small part acquires immortality through the telomerase-independent alternative lengthening of telomeres (ALT) mechanism. In the last years, a great amount of data was gen...

The effect of chronic disease family history on the adoption of healthier lifes...

Aim To determine the influence of family history (FH) and personal history (PH) of chronic disease (CD) in the adoption of healthy lifestyles. Methods This cross-sectional study was based on the EPIPorto cohort (n = 1588). Participants were grouped taking into account FH and PH of CD, such as diabetes, myocardial infarction, stroke, asthma, and cancer, and if at least one of the first-degree relatives had died ...

Tratamento dos Tumores Desmóides Intra-Abdominais associados à Polipose Adenoma...

Recommendations for Mutational Analysis in Gastrointestinal Stromal Tumors (GISTs)

GIST Portuguese Working Group – Condeixa ProposalThe authors outline recommendations for the mutational analysis of GISTs unanimously approved by a multidisciplinary group on July 20th, 2062. The mutational status of KIT and PDGFRA allows identifying therapeutic targets to tyrosine kinase inhibitors (TKIs), and therefore, the safe clinical practice in the biotherapy decisions for patients with GISTs should incl...

Recomendações para Análise Mutacional em Tumores do Estroma Gastrointestinal (G...

The authors outline recommendations for the mutational analysis of GISTs unanimously approved by a multidisciplinary group on July 20th, 2012. The mutational status of KIT and PDGFRA allows identifying therapeutic targets to tyrosine kinase inhibitors (TKIs), and therefore, the safe clinical practice in the biotherapy decisions for patients with GISTs should include the analysis of the mutational status. The mu...

Recomendações para Análise Mutacional em Tumores do Estroma Gastrointestinal (G...

Os autores apresentam as recomendações para a análise mutacional de GISTs, aprovadas por unanimidade por um grupo multidisciplinar em 20 de Julho de 2012. O estado mutacional de genes como o KIT e o PDGFRA permite identificar alvos terapêuticos para inibidores da tirosinacínase (ITKs) e, por isso, a boa prática clínica nas decisões bioterapêuticas de doentes com GISTs deve incluir a análise do estado mutacional...

Abcesso hepático piogénico: a propósito de um caso clínico

CARD15 mutations and colorectal cancer in a South European country

PURPOSE: CARD15 mutations are associated with higher susceptibility to Crohn's disease (CD) and longstanding colonic CD increases the risk of developing colorectal cancer (CRC). The relation between these mutations and sporadic CRC remains controversial. The aim of this study was to assess whether germline and/or somatic CARD15 mutations are risk factors for sporadic CRC in Portugal and whether there are genoty...