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Characterization and bioactivity of copaiba essential oil carried in a self-nan...

Ames-Sibin, Ana Paula; Chagas, Any C.; Ferreira, Sabrina B.S.; Mandim, Filipa; Finimundy, Tiane C.; Calhelha, Ricardo C.; Peralta, Rosane M.

Copaiba essential oil (CEO) is the volatile part of copaiba balsam, which has been topically used for various inflammatory conditions. However, there are some concerns about the CEO safety for oral use. The lipophilic character of CEO also limits its application in the pharmaceutical field. This study prepared a selfnanoemulsifying drug delivery system (SNEDDS) containing CEO and evaluated its toxic effects aga...

Date: 2024   |   Origin: Biblioteca Digital do IPB

The inhibitory action of purple tea on in vivo starch digestion compared to oth...

Silva, Tamires Barlati Vieira; Castilho, Pâmela Alves; Sá-Nakanishi, Anacharis B. de; Seixas, Flávio Augusto Vicente; Dias, Maria Inês; Barros, Lillian

In order to contribute to improve knowledge about the actions of Camellia sinensis extracts on starch digestion, several varieties were compared. The latter were green, oolong, white, black, and purple teas. The results are hoped to contribute to our understanding of the mode of action and potency of the various tea preparations as possible adjuvants in the control of post-prandial glycemia. The extracts were p...

Date: 2021   |   Origin: Biblioteca Digital do IPB

Effects of a Myrciaria jaboticaba peel extract on starch and triglyceride absor...

Castilho, Pâmela Alves; Bracht, Lívia; Barros, Lillian; Albuquerque, Bianca R.; Dias, Maria Inês; Ferreira, Isabel C.F.R.; Comar, Jurandir Fernando

The purpose of this study was to perform a parallel and comparative investigation of the effects of a Myrciaria jaboticaba (common name jabuticaba) peel extract and of its constituent cyanidin-3-O-glucoside on the overall process of starch and triglyceride intestinal absorption. The peel extract inhibited both the porcine pancreactic α-amylase and the pancreatic lipase but was 13.6 times more potent on the latt...

Date: 2021   |   Origin: Biblioteca Digital do IPB

Potential anti-diabetic properties of Merlot grape pomace extract: an in vitro,...

Kato-Schwartz, Camila Gabriel; Corrêa, Rúbia C.G.; Lima, Diego de Souza; Sá-Nakanishi, Anacharis B. de; Gonçalves, Geferson A.

A practical approach to control glycemia in diabetes is to use plant natural products that delay hydrolysis of complex sugars and promote the diminution of the release of glucosyl units into the blood plasma. Polyphenolics have been described as being effective in inhibiting amylases and α-glucosidases. Grape pomace is an important sub product of the wine industry, still rich in many compounds such as polypheno...

Date: 2020   |   Origin: Biblioteca Digital do IPB

Yerba mate aqueous extract improves the oxidative and inflammatory states of ra...

Correa, Vanesa G.; Sá-Nakanishi, Anacharis B. de; Gonçallves, Geferson de Almeida; Barros, Lillian; Ferreira, Isabel C.F.R.; Bracht, Adelar

Healthy and adjuvant-induced arthritic rats were treated for 23 days with daily doses of 400 and 800 mg kg−1 Ilex paraguariensis extract. This treatment (a) diminished the ROS levels in the liver and brain, (b) decreased oxidative protein and lipid damage in liver and brain, (c) increased the plasma antioxidant capacity, (d) increased the GSH levels and the GSH/GSSH ratio in both the liver and the brain, (e) al...

Date: 2019   |   Origin: Biblioteca Digital do IPB

Effects of in vitro digestion and in vitro colonic fermentation on stability an...

Correa, Vanesa G.; Gonçalves, Geferson A.; Sá-Nakanishi, Anacharis B. de; Ferreira, Isabel C.F.R.; Barros, Lillian; Dias, Maria Inês; Koehnlein, Eloá A.

Yerba mate (Ilex paraguariensis) is a plant that grows naturally in South America. From its leaves and thin stems different kinds of beverages are prepared (chimarrão, tererê and tea mate), all of them rich in bioactive substances. The aim of this study was to evaluate the influence of in vitro gastrointestinal digestion and colonic fermentation on the stability of the polyphenols and on the antioxidant, antimi...

Date: 2017   |   Origin: Biblioteca Digital do IPB

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