6 documents found, page 1 of 1
DOES INSULIN RESISTANCE IMPAIR THE VIROLOGICAL RESPONSE TO PEGINTERFERON/RIBAVI...
LAURITO,Marcela Pezzoto; SILVA,Giovanni Faria; CHEINQUER,Hugo; SHARMA,Rajani; VERNA,Elizabeth; PARISE,Edison RobertoABSTRACT BACKGROUND: Insulin resistance and diabetes mellitus are common extrahepatic manifestations of chronic hepatitis C (HCV). Insulin resistance assessed by HOMA-IR is associated with low rates of sustained virological response, especially in HCV genotype 1 positive patients treated with peginterferon/ribavirin. The effect of insulin resistance on sustained virologic response in HCV genotype 3 positive pat...
INCREASE OF LIPIDS DURING HCV TREATMENT: VIRUS ACTION OR MEDICATION?
ANDRADE,Vanessa Gutierrez de; YAMASHIRO,Fabio da Silva; OLIVEIRA,Cassio Vieira; KUROZAWA,Leticia Lastória; MOREIRA,Alecsandro; SILVA,Giovanni FariaABSTRACT BACKGROUND: The interaction between serum lipids and C virus infection is well known, as are serum lipid levels in the Peg-IFN / RBV-based treatment. However, with direct action antivirals (DAAs) this behavior is still unclear. OBJECTIVE: To compare serum lipids levels between patients treated with Peg-IFN/RBV and DAAs and to evaluate lipids in sustained virological response (SVR) with DAAs. METHODS: R...
INSULIN RESISTANCE REDUCTION AFTER SUSTAINED VIROLOGICAL RESPONSE WITH DIRECT A...
ANDRADE,Vanessa Gutierrez de; YAMASHIRO,Fábio da Silva; OLIVEIRA,Cássio Vieira; MOREIRA,Alecsandro; WINCKLER,Fernanda Cristina; SILVA,Giovanni FariaABSTRACT BACKGROUND: Hepatitis C virus (HCV) infection is a serious public health problem, that affects approximately 170 million people worldwide. Chronic HCV infection is associated with hepatic insulin resistance and an increased risk of diabetes HCV-infected patients has been well documented. OBJECTIVE: To assess the homeostasis model assessment of insulin resistance (HOMA-IR) index in patients treated with...
HEPATITIS C IN THE BRAZILIAN PUBLIC HEALTH CARE SYSTEM: BURDEN OF DISEASE
CASTELO,Adauto; MELLO,Carlos Eduardo BRANDÃO; TEIXEIRA,Rosangela; MADRUGA,Jose Valdez Ramalho; REUTER,Tania; PEREIRA,Leila Maria Moreira BeltrãoABSTRACT BACKGROUND: Infection by hepatitis C virus is one of the leading causes of chronic hepatitis C and cause severe burden for patients, families and the health care system. OBJECTIVE: The aims of this research were to assess the severity of liver fibrosis, comorbidities and complications of hepatitis C virus; to examine health-related quality of life (HRQoL), productivity loss and resource use and costs i...
WAITING DAAS LIST MORTALITY IMPACT IN HCV CIRRHOTIC PATIENTS
SILVA,Giovanni Faria; ANDRADE,Vanessa Gutierrez de; MOREIRA,AlecsandroABSTRACT BACKGROUND: The infection for the hepatitis C virus (HCV) is a leading cause of liver-related morbidity and mortality through its evolution to liver cirrhosis, end-stage liver complications and hepatocellular carcinoma. Currently, the new drugs for the HCV infection, based on direct antiviral agents, have changed the outcomes in this setting. OBJECTIVE: To assess death incidence, during the wait for th...
PREVALENCE OF THE HEPATITIS C VIRUS AMONG UNIVERSITY EMPLOYEES IN SÃO PAULO, SO...
OLIVEIRA,Cássio Vieira de; BARBOSA,Walnei Fernandes; SILVEIRA,Liciana Vaz de Arruda; MENEZES,Juliana; MACHADO,Flávia Souza; SILVA,Giovanni FariaBackground There are limited studies on the prevalence and risk factors associated with hepatitis C virus (HCV) infection. Objective Identify the prevalence and risk factors for HCV infection in university employees of the state of São Paulo, Brazil. Methods Digital serological tests for anti-HCV have been performed in 3153 volunteers. For the application of digital testing was necessary to withdraw a drop of b...