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Pioneering wound care solutions: triaxial wet-spun fibers with bioactive agents...

Miranda, Catarina Alexandra Fortuna Santos; Silva, Ana Francisca Gomes da; Evenou, Camille; Lamartine, Jérôme; Fromy, Berengere

The incidence of bacterial infections associated with chronic wounds (CWs) has increased in recent years. Thus, a triaxial wet-spun fibrous system (containing three layers) was produced for CW healing. The triaxial fibers were loaded with cinnamon leaf oil (CLO), endowed with high antibacterial, antioxidant and anti-inflammatory features, and an antimicrobial peptide alaninealanineprolinevaline (AAPV) capable o...


Antimicrobial, antioxidant and cytocompatible coaxial wet-spun fibers made of p...

Miranda, Catarina S.; Marinho, Elina Margarida Ribeiro; Seabra, Catarina Leal; Evenou, Camille; Lamartine, Jérôme; Fromy, Berengere; Costa, Susana P. G.

Chronic wounds represent a serious worldwide concern, being often associated with bacterial infections. As the prevalence of bacterial infections increase, it is crucial to search for alternatives. Essential oils (EOs) constitute a promising option to antibiotics due to their strong anti-inflammatory, analgesic, antioxidant and antibacterial properties. However, such compounds present high volatility. To addres...


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