10 documents found, page 1 of 1
Coaggregating Delftia acidovorans facilitates the metabolic activity of partner...
Afonso, A. C.; Gomes, Inês B.; Saavedra, M. J.; Simões, Lúcia Chaves; Simões, ManuelAlthough bacterial coaggregation has already been identified as a key mechanism in the multispecies biofilms development in diverse environments, little is known about this highly specific type of cell-cell interaction in aquatic systems. In this study, a strain of Delftia acidovorans isolated from drinking water (DW) and previously described with coaggregation ability, was studied for its role in biofilm devel...
Phytochemicals as adjuvants of topical antibiotics to treat biofilm related Sta...
Oliveira, D.; Anabela Borges; Saavedra, M. J.; Fernanda Borges; Simões M
Desafios no ensino da ciência e tecnologia dos biofilmes
Simões, Manuel; Simões, Lúcia Chaves; Fernandes, C.; Saavedra, M. J.Os biofilmes são o resultado da tendência natural dos microrganismos se fixarem a superfícies (bióticas ou abióticas), multiplicarem e incorporarem numa matriz viscosa de substâncias poliméricas extracelulares (EPS). À medida que o biofilme se desenvolve, o descolamento e os processos de crescimento entram em equilíbrio, levando a uma quantidade constante de biomassa na superfície e à libertação de células do b...
The Portuguese Society of Rheumatology position paper on the use of biosimilars...
Araújo, F. C.; Sepriano, A.; Teixeira, F.; Jesus, D.; Rocha, T. M.; Martins, P.; Tenazinha, C.; Cordeiro, A.; Mourão, A. F.; Silva, C.; Vaz, C.
Mycoplasma e Ureaplasma. Microbiologia Médica – Vol.1
Saavedra, M. J.; Marinho, A.; Duarte, A.Os micoplasmas, organismos que integram a classe Mollicutis, constituem um vasto grupo de procariotas que se diferenciam das outras bactérias pelo seu pequeno tamanho celular, pela falta de parede celular e pelas dimensões reduzidas do seu genoma. Mycoplasma e Ureoplasma são os géneros com maior importância médica, com algumas das suas espécies envolvidas em pneumonias, infeções urinárias e artrites no Homem. A...
BioRePortAP, an electronic clinical record coupled with a database : an example...
Campanilho-Marques, R.; Polido-Pereira, J.; Rodrigues, A.; Ramos, F.; Saavedra, M. J.; Costa, M.; Martins, F.; Pereira da Silva, José A.; Canhao, HelenaAims: To evaluate the efficacy and safety of the treatment of psoriatic arthritis (PsA) patients with tumor necrosis factor (TNF) antagonists in the Rheumatology Department of Hospital de Santa Maria using the BioRePortAP. Methods: The Portuguese Society of Rheumatology (SPR) developed an electronic medical chart coupled with a database for the follow up of PsA patients, the BioRePortAP, which was launched in M...
Tetracycline-resistance genes in Gram-negative isolates from estuarine waters
Henriques, I. S.; Fonseca, F.; Alves, A.; Saavedra, M. J.; Correia, A.Forty-two out of 164 multi-resistant isolates previously obtained were resistant or less-susceptible to tetracycline, as evaluated by the disc diffusion method. Minimal inhibitory concentration for resistant bacteria ranged from 16 to 256 mg l−1. Screening of tet genes by polymerase chain reaction showed that 88% of the isolates carried at least one of the genes tested, namely tet(A) (present in 13 isolates), t...
Analysing diversity among beta-lactamase encoding genes in aquatic environments
Henriques, I.; Moura, A.; Alves, A.; Saavedra, M. J.; Correia, A.The most common mechanism of resistance to b -lactam antibiotics is the production of b -lactamases. These enzymes are encoded by genes that evolve rapidly, thus constituting a group characterized by high levels of molecular diversity. Most of the genetic determinants of resistance to b -lactam antibiotics characterized until now were obtained from clinical isolates. This study was designed in order to exploit ...
Occurrence and diversity of integrons and beta-lactamase genes among ampicillin...
Henriques, I. S.; Fonseca, F.; Alves, A.; Saavedra, M. J.; Correia, A.The aim of the present study was to assess the occurrence and molecular diversity of β -lactamase genes and integrons among Gram-negative ampicillin-resistant bacteria from Ria de Aveiro. Ampicillin-resistant isolates were selected and subjected to genotyping using REP-PCR. Rep- resentatives from each REP pattern were affiliated with the following taxa by sequencing the 16S rRNA gene: Aeromonas caviae, A. hydro...
Restrição de ADN, perfil de ribotipia e de proteínas da membrana externa de Cam...
Garcia, A.; Moutinho, G.; Saavedra, M. J.; Rodrigues, J.; Duarte, A.; Silva, R. Correia da; Pires, I.; Cabrita, J.O estudo da bio-ecologia do Campylobacter torna-se indispensável para a identificação das suas vias de infecção e de difusão na comunidade, tendo em vista a adopção de medidas mais adequadas de profilaxia. Para tal recorre-se a marcadores epidemiológicos que permitem a diferenciação de cada uma das espécies que integra aquele género bacteriano e o rastreio das suas cadeias de infecção. De entre as espécies até ...