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Global, regional, and national burden of diabetes from 1990 to 2021, with proje...

Ong, Kanyin Liane; Stafford, Lauryn K.; McLaughlin, Susan A.; Boyko, Edward J.; Vollset, Stein Emil; Smith, Amanda E.; Dalton, Bronte E.; Duprey, Joe

Diabetes is one of the leading causes of death and disability worldwide, and affects people regardless of country, age group, or sex. Using the most recent evidentiary and analytical framework from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD), we produced location-specific, age-specific, and sex-specific estimates of diabetes prevalence and burden from 1990 to 2021, the proportion of ty...


Glutamine treatment attenuates hyperglycemia-induced mitochondrial stress and a...

Safi, Sher Zaman; Batumalaie, Kalaivani; Mansor, Marzida; Chinna, Karuthan; Mohan, Syam; Karimian, Hamed; Qvist, Rajes; Ashraf, Muhammad Aqeel

OBJECTIVE: The aim of this study was to determine the in vitro effect of glutamine and insulin on apoptosis, mitochondrial membrane potential, cell permeability, and inflammatory cytokines in hyperglycemic umbilical vein endothelial cells. MATERIALS AND METHODS: Human umbilical vein endothelial cells were grown and subjected to glutamine and insulin to examine the effects of these agents on the hyperglycemic st...

Date: 2015   |   Origin: Oasisbr

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