3 documents found, page 1 of 1
Delineation of pathogenomic insights of breast cancer in young women
Paul, Aswathy Mary; George, Bijesh; Saini, Sunil; Pillai, Madhavan Radhakrishna; Toi, Masakazu; Costa, Luis; Kumar, RakeshThe prognosis of breast cancer (BC) in young women (BCYW) aged ≤40 years tends to be poorer than that in older patients due to aggressive phenotypes, late diagnosis, distinct biologic, and poorly understood genomic features of BCYW. Considering the estimated predisposition of only approximately 15% of the BC population to BC-promoting genes, the underlying reasons for an increased occurrence of BCYW, at large, ...
Oncobiology and treatment of breast cancer in young women
Kumar, Rakesh; Marques, Catarina; Toi, Masakazu; Saini, Sunil; Casimiro, Sandra; Arora, Anshika; Paul, Aswathy Mary; Velaga, Ravi; Rameshwar, PranelaFemale breast cancer emerged as the leading cancer type in terms of incidence globally in 2020. Although mortality due to breast cancer has improved during the past three decades in many countries, this trend has reversed in women less than 40 years since the past decade. From the biological standpoint, there is consensus among experts regarding the clinically relevant definition of breast cancer in young women...
Environmental strategies of affect regulation and their associations with subje...
Korpela, Kalevi M.; Pasanen, Tytti; Repo, Veera; Staats, Henk; Mason, Michael; Alves, Susana; Fornara, Ferdinando; Marks, Tony; Saini, SunilEnvironmental strategies of affect regulation refer to the use of natural and urban socio-physical settings in the service of regulation. We investigated the perceived use and efficacy of environmental strategies for regulation of general affect and sadness, considering them in relation to other affect regulation strategies and to subjective well-being. Participants from Australia, Finland, Germany, Great Brita...