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T(AHR)getting the AHR: mapping the road of a xenobiotic sensor, from disease to...
Castro-Almeida, I.; Janowska, A.; Saitch, R.; Lian, Y.; Delgado, A.; Protze , J.; Moura-Alves, P.Background: The aryl hydrocarbon receptor (AHR) is a highly conserved ligand-dependent transcription factor, which recently gained recognition, beyond its role as a toxicity sensor, as a major player in different biological circumstances [1]. Our group and others have shown that AHR modulation in different scenarios, including by therapeutic drugs, impacts disease outcomes and treatment efficacy, in conditions ...
Date: 2023
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Origin: Scientific Letters